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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG5893-RA through 18771 annotations produced 1 hits

fish-hook (D):

Annotation Number : CG5893
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000411
Gbrowse : chr3L:14168700-14171720 (-) // 100.0 //
Probeset : 1628604_at
Accessions : protein= NP_524066;, nucleotide= NM_079342;
Pathway : DNA-dependent // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development //
Interpro : DNA-dependent // inferred from direct assay /// 0060810 // intracellular mRNA localization involved in pattern specific
FlyMine data for FBgn0000411.
BDGP gene expression has embryonic in situ data for D: 49 pix of staining in 29 body parts.
Homophila reports that CG5893 is a close match (2e-17) to human gene SOX18;HLTS (NP_060889), a gene associated with Hypotrichosis-lymphedema-telangiectasia syndrome, 607823 (3).
BioGrid reports that CG5893 interacts with CG9511 CG18024 CG18024 CG9885 CG11551 CG7771 CG10037 .
TRiP has 2 RNAi stocks for FBgn0000411 available for purchase.
VDRC has 3 RNAi stocks for FBgn0000411 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain383 74 of 413.60Up
Head98 74 of 4 3.50Up
Eye17 24 of 4 0.62Down
Thoracicoabdominal ganglion73 54 of 4 2.60Up
Salivary gland2441 554 of 486.28Up
Crop38 44 of 4 1.40None
Midgut3 10 of 4 0.10Down
Tubule2 00 of 4 0.10Down
Hindgut180 84 of 4 6.40Up
Heart4 10 of 4 0.17Down
Fat body8 53 of 4 0.31Down
Ovary1 10 of 4 0.10Down
Testis50 34 of 4 1.80Up
Male accessory glands2 00 of 4 0.10Down
Virgin spermatheca6 10 of 4 0.22Down
Mated spermatheca4 10 of 4 0.15Down
Adult carcass19 51 of 4 0.70None
Larval CNS410 404 of 414.50Up
Larval Salivary gland360 334 of 412.73Up
Larval midgut1 00 of 4 0.06Down
Larval tubule2 00 of 4 0.10Down
Larval hindgut694 614 of 424.54Up
Larval fat body8 21 of 4 0.30Down
Larval trachea7 42 of 4 0.26Down
Larval carcass36 14 of 4 1.28None
S2 cells (growing)0 00 of 4 0.03Down
Whole fly28 34 of 4

Looking for CG5893-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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