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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG6113-RA through 18771 annotations produced 1 hits

CG6113 (Lip4):

Annotation Number : CG6113
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0032264
Gbrowse : chr2L:10529416-10531561 (+) // 100.0 //
Probeset : 1624505_at
Accessions : protein= NP_609418;, nucleotide= NM_135574;
Interpro : 0004806 // triglyceride lipase activity // inferred from sequence or structural similarity /// 0004806 // triglyceride l
FlyMine data for FBgn0032264.
BDGP gene expression has embryonic in situ data for CG6113: 25 pix of staining in 2 body parts.
Homophila reports that CG6113 is a close match (3e-66) to human gene LIPA (NP_000226), a gene associated with Cholesteryl ester storage disease (3);Wolman disease (3).
TRiP has 1 RNAi stocks for FBgn0032264 available for purchase.
VDRC has 3 RNAi stocks for FBgn0032264 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain13 14 of 4 0.20Down
Head142 104 of 4 1.70Up
Eye83 124 of 4 0.97None
Thoracicoabdominal ganglion18 24 of 4 0.20Down
Salivary gland8 40 of 4 0.10Down
Crop907 494 of 410.60Up
Midgut71 34 of 4 0.80None
Tubule9 20 of 4 0.10Down
Hindgut321 224 of 4 3.80Up
Heart431 184 of 4 5.06Up
Fat body563 1334 of 4 6.61Up
Ovary27 24 of 4 0.30Down
Testis26 34 of 4 0.30Down
Male accessory glands3 10 of 4 0.00Down
Virgin spermatheca395 184 of 4 4.63Up
Mated spermatheca332 444 of 4 3.89Up
Adult carcass300 164 of 4 3.50Up
Larval CNS84 134 of 4 1.00None
Larval Salivary gland20 14 of 4 0.24Down
Larval midgut109 214 of 4 1.29None
Larval tubule12 22 of 4 0.10Down
Larval hindgut76 104 of 4 0.90None
Larval fat body822 814 of 4 9.60Up
Larval trachea6 40 of 4 0.08Down
Larval carcass11 32 of 4 0.13Down
S2 cells (growing)57 74 of 4 0.67Down
Whole fly85 74 of 4

Looking for CG6113-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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