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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG6146-RA through 18771 annotations produced 1 hits



topoisomerase I (Top1):

Annotation Number : CG6146
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004924
Gbrowse : chrX:15213524-15220302 (+) // 100.0 //
Probeset : 1634104_a_at
Accessions : protein= NP_001014742; /// NP_511161; /// NP_727841;, nucleotide= NM_001014742; /// NM_078606; /// NM_167435;
Pathway : "0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005
Interpro : core complex // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005703
FlyMine data for FBgn0004924.
Homophila reports that CG6146 is a close match (0) to human gene TOP1 (NP_003277), a gene associated with DNA topoisomerase I, camptothecin-resistant (3).
BioGrid reports that CG6146 interacts with CG9060 .
TRiP has 1 RNAi stocks for FBgn0004924 available for purchase.
VDRC has 1 RNAi stocks for FBgn0004924 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain71 ± 14 of 4 0.20Down
Head63 ± 104 of 4 0.20Down
Eye26 ± 13 of 4 0.08Down
Thoracicoabdominal ganglion58 ± 103 of 4 0.20Down
Salivary gland115 ± 30 of 4 0.36Down
Crop101 ± 44 of 4 0.30Down
Midgut90 ± 14 of 4 0.30Down
Tubule84 ± 74 of 4 0.30Down
Hindgut74 ± 32 of 4 0.20Down
Heart55 ± 14 of 4 0.17Down
Fat body128 ± 164 of 4 0.40Down
Ovary974 ± 204 of 4 3.00Up
Testis167 ± 54 of 4 0.50Down
Male accessory glands116 ± 114 of 4 0.40Down
Virgin spermatheca40 ± 22 of 4 0.13Down
Mated spermatheca44 ± 33 of 4 0.14Down
Adult carcass114 ± 102 of 4 0.40Down
Larval CNS108 ± 124 of 4 0.34Down
Larval Salivary gland151 ± 144 of 4 0.47Down
Larval midgut71 ± 14 of 4 0.22Down
Larval tubule106 ± 34 of 4 0.30Down
Larval hindgut110 ± 64 of 4 0.35Down
Larval fat body137 ± 114 of 4 0.40Down
Larval trachea87 ± 114 of 4 0.27Down
Larval carcass125 ± 93 of 4 0.39Down
S2 cells (growing)215 ± 54 of 4 0.67Down
Whole fly320 ± 334 of 4

Looking for CG6146-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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