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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG6385-RA through 18771 annotations produced 1 hits



(CG6385):

Annotation Number : CG6385
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0034276
Gbrowse : chr2R:13641051-13643923 (-) // 100.0 //
Probeset : 1639819_at
Accessions : protein= NP_611263;, nucleotide= NM_137419;
Pathway : 0005737 // cytoplasm // inferred from electronic annotation
Interpro : 0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0008480 // sarcosine dehydrogenase
FlyMine data for FBgn0034276.
Homophila reports that CG6385 is a close match (2e-105) to human gene DMGDH;DMGDHD (NP_037523), a gene associated with Dimethylglycine dehydrogenase deficiency, 605850 (3).
VDRC has 2 RNAi stocks for FBgn0034276 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain6 ± 01 of 4 0.20Down
Head110 ± 144 of 4 4.30Up
Eye86 ± 354 of 4 3.38None
Thoracicoabdominal ganglion7 ± 11 of 4 0.30Down
Salivary gland8 ± 60 of 4 0.31None
Crop8 ± 00 of 4 0.30Down
Midgut16 ± 20 of 4 0.70None
Tubule8 ± 10 of 4 0.30Down
Hindgut15 ± 14 of 4 0.60None
Heart72 ± 44 of 4 2.85Up
Fat body229 ± 614 of 4 8.96Up
Ovary3 ± 02 of 4 0.10Down
Testis1 ± 00 of 4 0.10Down
Male accessory glands5 ± 20 of 4 0.20Down
Virgin spermatheca420 ± 314 of 416.44Up
Mated spermatheca218 ± 364 of 4 8.55Up
Adult carcass85 ± 104 of 4 3.30Up
Larval CNS2 ± 10 of 4 0.11Down
Larval Salivary gland29 ± 04 of 4 1.14None
Larval midgut9 ± 10 of 4 0.36Down
Larval tubule7 ± 11 of 4 0.30Down
Larval hindgut33 ± 84 of 4 1.31None
Larval fat body1155 ± 1304 of 445.20Up
Larval trachea11 ± 52 of 4 0.47Down
Larval carcass11 ± 20 of 4 0.46Down
S2 cells (growing)3 ± 00 of 4 0.14Down
Whole fly25 ± 34 of 4

Looking for CG6385-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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