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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG6687-RA through 18771 annotations produced 1 hits

Dm-serpin-88Eb (Spn88Eb):

Annotation Number : CG6687
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0038299
Gbrowse : chr3R:11032417-11034484 (-) // 100.0 //
Probeset : 1636946_at
Accessions : protein= NP_650427;, nucleotide= NM_142170;
Interpro : 0004867 // serine-type endopeptidase inhibitor activity // inferred from sequence or structural similarity /// 0004867 /
FlyMine data for FBgn0038299.
Homophila reports that CG6687 is a close match (2e-13) to human gene CBP2;PPROM;SERPINH2 (NP_001226), a gene associated with {Preterm premature rupture of the membranes, susceptibility to}, 610504 (3).
VDRC has 2 RNAi stocks for FBgn0038299 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain14 24 of 4 0.10Down
Head416 404 of 4 2.90Up
Eye219 514 of 4 1.53None
Thoracicoabdominal ganglion23 24 of 4 0.20Down
Salivary gland19 12 of 4 0.13Down
Crop22 24 of 4 0.20Down
Midgut22 33 of 4 0.20Down
Tubule23 43 of 4 0.20Down
Hindgut68 34 of 4 0.50Down
Heart991 414 of 4 6.91Up
Fat body2228 2004 of 415.54Up
Ovary8 21 of 4 0.10Down
Testis11 04 of 4 0.10Down
Male accessory glands12 41 of 4 0.10Down
Virgin spermatheca2109 1294 of 414.71Up
Mated spermatheca1829 1734 of 412.75Up
Adult carcass841 374 of 4 5.90Up
Larval CNS7 12 of 4 0.05Down
Larval Salivary gland45 24 of 4 0.32Down
Larval midgut18 14 of 4 0.13Down
Larval tubule20 23 of 4 0.10Down
Larval hindgut59 84 of 4 0.42Down
Larval fat body1967 1964 of 413.70Up
Larval trachea18 142 of 4 0.13Down
Larval carcass28 24 of 4 0.20Down
S2 cells (growing)109 84 of 4 0.76None
Whole fly143 234 of 4

Looking for CG6687-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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