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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG6716-RB through 18771 annotations produced 1 hits

paired (prd):

Annotation Number : CG6716
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0003145
Gbrowse : chr2L:12082996-12086456 (-) // 100.0 //
Probeset : 1633879_a_at
Accessions : protein= NP_523556; /// NP_723721;, nucleotide= NM_078832; /// NM_164990;
Pathway : DNA-dependent // inferred from electronic annotation /// 0006355 // regulation of transcription
Interpro : DNA-dependent // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from el
FlyMine data for FBgn0003145.
BDGP gene expression has embryonic in situ data for prd: 92 pix of staining in 14 body parts.
Homophila reports that CG6716 is a close match (9e-11) to human gene KTCN;PPCD;PPD;RINX;VSX1 (NP_955457), a gene associated with Corneal dystrophy, hereditary polymorphous posterior, 122000 (3);Craniofacial anomalies, empty sella turcica, corneal endothelial changes, and abnormal retinal and auditory bipolar cells (3);Keratoconus, 148300 (3).
BioGrid reports that CG6716 interacts with CG10798 CG3388 CG3388 CG3388 CG3938 .
TRiP has 1 RNAi stocks for FBgn0003145 available for purchase.
VDRC has 1 RNAi stocks for FBgn0003145 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1 10 of 4 0.10Down
Head5 10 of 4 0.20Down
Eye2 10 of 4 0.06Down
Thoracicoabdominal ganglion3 10 of 4 0.10Down
Salivary gland9 30 of 4 0.28Down
Crop5 21 of 4 0.20Down
Midgut3 10 of 4 0.10Down
Tubule5 00 of 4 0.10Down
Hindgut3 20 of 4 0.10Down
Heart2 00 of 4 0.06Down
Fat body14 72 of 4 0.43Down
Ovary3 00 of 4 0.10Down
Testis25 24 of 4 0.70None
Male accessory glands3050 834 of 488.60Up
Virgin spermatheca12 12 of 4 0.35Down
Mated spermatheca16 52 of 4 0.47Down
Adult carcass9 10 of 4 0.30Down
Larval CNS7 31 of 4 0.22Down
Larval Salivary gland9 00 of 4 0.29Down
Larval midgut4 10 of 4 0.14Down
Larval tubule4 10 of 4 0.10Down
Larval hindgut4 00 of 4 0.14Down
Larval fat body11 10 of 4 0.30Down
Larval trachea0 00 of 4 0.02Down
Larval carcass1 00 of 4 0.04Down
S2 cells (growing)3 10 of 4 0.11Down
Whole fly34 54 of 4

Looking for CG6716-RB. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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