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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG6800-RA through 18771 annotations produced 1 hits

CDK7-like (CG6800):

Annotation Number : CG6800
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0038902
Gbrowse : chr3R:17601859-17602935 (+) // 100.0 //
Probeset : 1624479_at
Accessions : protein= NP_650984;, nucleotide= NM_142727;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0038902.
Homophila reports that CG6800 is a close match (8e-11) to human gene ERBB2;HER2;NEU;NGL (NP_004439), a gene associated with Adenocarcinoma of lung, somatic, 211980 (3);Gastric cancer, somatic, 137215 (3);Glioblastoma, somatic, 137800 (3);Ovarian cancer, somatic, (3).
BioGrid reports that CG6800 interacts with CG15676 CG9046 CG17508 CG5708 CG2944 CG7948 CG5568 CG5731 CG31811 CG4221 CG5009 CG13900 .
VDRC has 3 RNAi stocks for FBgn0038902 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain16 24 of 4 4.00Up
Head10 11 of 4 2.50Up
Eye2 00 of 4 0.63None
Thoracicoabdominal ganglion17 14 of 4 4.20Up
Salivary gland7 31 of 4 1.96None
Crop7 20 of 4 1.80None
Midgut14 22 of 4 3.60Up
Tubule6 00 of 4 1.70Up
Hindgut7 21 of 4 2.00None
Heart1 00 of 4 0.36None
Fat body2 10 of 4 0.73None
Ovary3 00 of 4 0.80None
Testis6 00 of 4 1.60None
Male accessory glands3 00 of 4 0.80None
Virgin spermatheca4 10 of 4 1.09None
Mated spermatheca7 00 of 4 1.84Up
Adult carcass7 30 of 4 1.80None
Larval CNS8 03 of 4 2.22Up
Larval Salivary gland5 10 of 4 1.40None
Larval midgut9 30 of 4 2.33None
Larval tubule5 00 of 4 1.30None
Larval hindgut3 10 of 4 0.92None
Larval fat body10 23 of 4 2.70Up
Larval trachea6 20 of 4 1.63None
Larval carcass5 00 of 4 1.30None
S2 cells (growing)4 10 of 4 1.03None
Whole fly4 10 of 4

Looking for CG6800-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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