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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG6811-RA through 18771 annotations produced 1 hits

RhoGAP68F (RhoGAP68F):

Annotation Number : CG6811
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0036257
Gbrowse : chr3L:12131972-12136482 (+) // 100.0 //
Probeset : 1634034_at
Accessions : protein= NP_648552;, nucleotide= NM_140295;
Pathway : 0005622 // intracellular // inferred from electronic annotation
Interpro : 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005100 // Rho GTPase activator activity
FlyMine data for FBgn0036257.
BDGP gene expression has embryonic in situ data for RhoGAP68F: 19 pix of staining in 6 body parts.
Homophila reports that CG6811 is a close match (7e-11) to human gene CHN1;CHN;ARHGAP2;RHOGAP2;DURS2 (NP_001813), a gene associated with Duane retraction syndrome 2, 604356 (3).
BioGrid reports that CG6811 interacts with CG10078 CG13510 CG5825 CG7296 CG6663 CG18806 CG14048 CG6164 CG15861 CG3026 CG11182 CG11777 CG11138 CG2944 CG32505 CG5860 CG5473 CG31000 CG5571 CG32045 CG2064 CG1773 CG18745 CG10246 CG5390 CG31811 CG3658 CG16892 CG31646 CG18031 CG6753 CG4921 CG8181 .
TRiP has 2 RNAi stocks for FBgn0036257 available for purchase.
VDRC has 3 RNAi stocks for FBgn0036257 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain248 34 of 4 1.40Up
Head169 84 of 4 1.00None
Eye116 24 of 4 0.67Down
Thoracicoabdominal ganglion213 24 of 4 1.20Up
Salivary gland178 54 of 4 1.02None
Crop311 114 of 4 1.80Up
Midgut290 44 of 4 1.70Up
Tubule481 174 of 4 2.80Up
Hindgut200 74 of 4 1.10None
Heart259 224 of 4 1.49Up
Fat body349 364 of 4 2.00Up
Ovary241 14 of 4 1.40Up
Testis75 34 of 4 0.40Down
Male accessory glands128 64 of 4 0.70Down
Virgin spermatheca370 174 of 4 2.12Up
Mated spermatheca322 254 of 4 1.85Up
Adult carcass220 114 of 4 1.30Up
Larval CNS202 84 of 4 1.16Up
Larval Salivary gland139 44 of 4 0.80Down
Larval midgut446 464 of 4 2.56Up
Larval tubule992 114 of 4 5.70Up
Larval hindgut237 204 of 4 1.36Up
Larval fat body499 404 of 4 2.90Up
Larval trachea210 204 of 4 1.21Up
Larval carcass118 134 of 4 0.68Down
S2 cells (growing)221 34 of 4 1.27Up
Whole fly174 84 of 4

Looking for CG6811-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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