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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG6816-RB through 18771 annotations produced 2 hits



Cytochrome P450 17C (Cyp18a1):

Annotation Number : CG6816
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010383
Gbrowse : chrX:18583105-18586778 (-) // 100.0 //
Probeset : 1641022_a_at
Accessions : protein= NP_523403; /// NP_728191;, nucleotide= NM_078679; /// NM_167628;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0010383.
BDGP gene expression has embryonic in situ data for Cyp18a1: 30 pix of staining in 18 body parts.
Homophila reports that CG6816 is a close match (4e-11) to human gene CYP11A;P450SCC (NP_000772), a gene associated with Adrenal insufficiency, congenital with or without 46, XY sex reversal (3);Lipoid congenital adrenal hyperplasia, 201710 (3).
VDRC has 3 RNAi stocks for FBgn0010383 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain21 ± 24 of 4 0.40Down
Head74 ± 54 of 4 1.40Up
Eye51 ± 54 of 4 0.97None
Thoracicoabdominal ganglion19 ± 24 of 4 0.40Down
Salivary gland16 ± 61 of 4 0.30Down
Crop14 ± 22 of 4 0.30Down
Midgut14 ± 11 of 4 0.30Down
Tubule15 ± 13 of 4 0.30Down
Hindgut26 ± 14 of 4 0.50Down
Heart97 ± 124 of 4 1.84Up
Fat body250 ± 584 of 4 4.73Up
Ovary43 ± 34 of 4 0.80None
Testis5 ± 10 of 4 0.10Down
Male accessory glands8 ± 30 of 4 0.20Down
Virgin spermatheca301 ± 324 of 4 5.69Up
Mated spermatheca168 ± 254 of 4 3.19Up
Adult carcass143 ± 84 of 4 2.70Up
Larval CNS11 ± 23 of 4 0.22Down
Larval Salivary gland15 ± 20 of 4 0.29Down
Larval midgut12 ± 11 of 4 0.23Down
Larval tubule8 ± 20 of 4 0.20Down
Larval hindgut12 ± 01 of 4 0.23Down
Larval fat body14 ± 22 of 4 0.30Down
Larval trachea167 ± 624 of 4 3.17Up
Larval carcass245 ± 214 of 4 4.64Up
S2 cells (growing)9 ± 01 of 4 0.17Down
Whole fly53 ± 54 of 4



Cytochrome P450 17C (Cyp18a1):

Annotation Number : CG6816
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010383
Gbrowse : chrX:18582569-18586778 (-) // 100.0 //
Probeset : 1631300_at
Accessions : protein= NP_523403; /// NP_728191;, nucleotide= NM_078679; /// NM_167628;
Pathway : 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane //
Interpro : 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred fro
FlyMine data for FBgn0010383.
BDGP gene expression has embryonic in situ data for Cyp18a1: 30 pix of staining in 18 body parts.
Homophila reports that CG6816 is a close match (4e-11) to human gene CYP11A;P450SCC (NP_000772), a gene associated with Adrenal insufficiency, congenital with or without 46, XY sex reversal (3);Lipoid congenital adrenal hyperplasia, 201710 (3).
VDRC has 3 RNAi stocks for FBgn0010383 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain20 ± 24 of 4 0.20Down
Head122 ± 84 of 4 1.30Up
Eye108 ± 194 of 4 1.14None
Thoracicoabdominal ganglion19 ± 24 of 4 0.20Down
Salivary gland17 ± 50 of 4 0.18Down
Crop12 ± 21 of 4 0.10Down
Midgut4 ± 10 of 4 0.00Down
Tubule8 ± 10 of 4 0.10Down
Hindgut19 ± 12 of 4 0.20Down
Heart244 ± 224 of 4 2.56Up
Fat body525 ± 624 of 4 5.50Up
Ovary90 ± 64 of 4 0.90None
Testis3 ± 10 of 4 0.00Down
Male accessory glands1 ± 00 of 4 0.00Down
Virgin spermatheca1126 ± 1324 of 411.80Up
Mated spermatheca660 ± 914 of 4 6.92Up
Adult carcass211 ± 74 of 4 2.20Up
Larval CNS15 ± 34 of 4 0.17Down
Larval Salivary gland13 ± 21 of 4 0.14Down
Larval midgut6 ± 11 of 4 0.06Down
Larval tubule6 ± 22 of 4 0.10Down
Larval hindgut11 ± 24 of 4 0.12Down
Larval fat body3 ± 10 of 4 0.00Down
Larval trachea424 ± 1754 of 4 4.44Up
Larval carcass503 ± 434 of 4 5.27Up
S2 cells (growing)2 ± 00 of 4 0.03Down
Whole fly95 ± 64 of 4

Looking for CG6816-RB. 2 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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