FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG7186-RA through 18771 annotations produced 1 hits

Sak kinase (SAK):

Annotation Number : CG7186
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0026371
Gbrowse : chr3L:21505240-21508984 (-) // 100.0 //
Probeset : 1629805_at
Accessions : protein= NP_649324;, nucleotide= NM_141067;
Pathway : 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // non-trace
FlyMine data for FBgn0026371.
BDGP gene expression has embryonic in situ data for SAK: 22 pix of staining in 7 body parts.
Homophila reports that CG7186 is a close match (8e-11) to human gene MTC;NTRK1;TRKA (NP_002520), a gene associated with Insensitivity to pain, congenital, with anhidrosis, 256800 (3);Medullary thyroid carcinoma, familial, 155240 (3).
BioGrid reports that CG7186 interacts with CG13510 CG5825 CG14119 CG32381 CG15043 CG15676 CG15861 CG9046 CG14534 CG15006 CG13558 CG2948 CG17508 CG5708 CG14387 CG11182 CG17515 CG7281 CG11138 CG2944 CG14816 CG13806 CG32139 CG32045 CG5072 CG7948 CG11525 CG5568 CG5731 CG15218 CG1034 CG31679 CG18745 CG2865 CG12723 CG31811 CG16892 CG8667 CG18273 CG9930 CG8272 CG15112 CG11486 CG4184 CG13900 CG17964 CG8676 CG1765 CG5003 CG4851 CG3612 CG30497 CG10395 CG8181 .
TRiP has 1 RNAi stocks for FBgn0026371 available for purchase.
VDRC has 2 RNAi stocks for FBgn0026371 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	24 ± 0	4 of 4	2.10	Up
Head	15 ± 1	4 of 4	1.30	None
Eye	16 ± 1	4 of 4	1.34	None
Thoracicoabdominal ganglion	26 ± 1	4 of 4	2.20	Up
Salivary gland	55 ± 7	4 of 4	4.57	Up
Crop	35 ± 0	4 of 4	3.00	Up
Midgut	44 ± 4	4 of 4	3.70	Up
Tubule	13 ± 1	3 of 4	1.10	None
Hindgut	20 ± 2	4 of 4	1.70	Up
Heart	10 ± 2	2 of 4	0.87	None
Fat body	14 ± 1	4 of 4	1.19	None
Ovary	8 ± 1	4 of 4	0.70	None
Testis	5 ± 0	3 of 4	0.50	None
Male accessory glands	34 ± 0	4 of 4	2.90	Up
Virgin spermatheca	15 ± 1	4 of 4	1.25	None
Mated spermatheca	15 ± 2	4 of 4	1.28	None
Adult carcass	10 ± 0	1 of 4	0.80	None
Larval CNS	90 ± 17	4 of 4	7.49	Up
Larval Salivary gland	47 ± 6	4 of 4	3.95	Up
Larval midgut	45 ± 4	4 of 4	3.80	Up
Larval tubule	37 ± 1	4 of 4	3.10	Up
Larval hindgut	39 ± 2	4 of 4	3.25	Up
Larval fat body	10 ± 1	2 of 4	0.90	None
Larval trachea	46 ± 1	4 of 4	3.88	Up
Larval carcass	24 ± 0	4 of 4	2.01	Up
S2 cells (growing)	31 ± 0	4 of 4	2.60	Up
Whole fly	12 ± 2	4 of 4

Looking for CG7186-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720