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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG7722-RA through 18771 annotations produced 1 hits

Serpin 47C (Spn47C):

Annotation Number : CG7722
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033574
Gbrowse : chr2R:6827689-6829171 (-) // 100.0 //
Probeset : 1623612_at
Accessions : protein= NP_001163116; /// NP_610633;, nucleotide= NM_001169645; /// NM_136789;
Interpro : 0004867 // serine-type endopeptidase inhibitor activity // inferred from sequence or structural similarity /// 0004867 /
FlyMine data for FBgn0033574.
BDGP gene expression has embryonic in situ data for CG7722: 4 pix of staining in 1 body parts.
Homophila reports that CG7722 is a close match (6e-11) to human gene C1NH;HAE1;HAE2;SERPING1 (NP_001027466), a gene associated with Angioedema, hereditary, 106100 (3).
VDRC has 2 RNAi stocks for FBgn0033574 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain3 02 of 4 0.10Down
Head225 184 of 4 3.40Up
Eye329 314 of 4 4.90Up
Thoracicoabdominal ganglion5 11 of 4 0.10Down
Salivary gland7 30 of 4 0.11Down
Crop96 134 of 4 1.40None
Midgut3 00 of 4 0.00Down
Tubule3 00 of 4 0.10Down
Hindgut58 94 of 4 0.90None
Heart5 02 of 4 0.08Down
Fat body10 33 of 4 0.16Down
Ovary2 00 of 4 0.00Down
Testis538 164 of 4 8.00Up
Male accessory glands5 10 of 4 0.10Down
Virgin spermatheca17 24 of 4 0.26Down
Mated spermatheca35 54 of 4 0.53Down
Adult carcass157 64 of 4 2.30Up
Larval CNS2 12 of 4 0.04Down
Larval Salivary gland2 00 of 4 0.04Down
Larval midgut13 24 of 4 0.20Down
Larval tubule1 00 of 4 0.00Down
Larval hindgut51 84 of 4 0.77None
Larval fat body38 173 of 4 0.60None
Larval trachea15 64 of 4 0.24Down
Larval carcass139 254 of 4 2.08None
S2 cells (growing)2 00 of 4 0.04Down
Whole fly67 34 of 4

Looking for CG7722-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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