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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG7727-RA through 18771 annotations produced 1 hits

beta-amyloid-protein-precursor-like (Appl):

Annotation Number : CG7727
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000108
Gbrowse : chrX:425651-472163 (+) // 99.83 //
Probeset : 1624033_at
Accessions : protein= NP_476626;, nucleotide= NM_057278;
Pathway : 0005576 // extracellular region // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct ass
Interpro : 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical inter
FlyMine data for FBgn0000108.
BDGP gene expression has embryonic in situ data for Appl: 9 pix of staining in 4 body parts.
Homophila reports that CG7727 is a close match (3e-27) to human gene AAA;AD1;APP;CVAP (NP_958817), a gene associated with Alzheimer disease-1, APP-related (3);Amyloidosis, cerebroarterial, Dutch type (3);Amyloidosis, cerebroarterial, Iowa type, 605714 (3).
BioGrid reports that CG7727 interacts with CG7765 CG7765 CG5433 CG17299 CG12348 CG12348 CG10751 CG1200 CG1200 .
TRiP has 2 RNAi stocks for FBgn0000108 available for purchase.
VDRC has 3 RNAi stocks for FBgn0000108 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1555 554 of 418.20Up
Head632 544 of 4 7.40Up
Eye690 664 of 4 8.07Up
Thoracicoabdominal ganglion1273 464 of 414.90Up
Salivary gland12 12 of 4 0.14Down
Crop7 11 of 4 0.10Down
Midgut7 11 of 4 0.10Down
Tubule6 01 of 4 0.10Down
Hindgut7 23 of 4 0.10Down
Heart9 04 of 4 0.11Down
Fat body14 84 of 4 0.17Down
Ovary3 00 of 4 0.00Down
Testis2 01 of 4 0.00Down
Male accessory glands6 00 of 4 0.10Down
Virgin spermatheca13 13 of 4 0.16Down
Mated spermatheca17 53 of 4 0.20Down
Adult carcass39 84 of 4 0.50Down
Larval CNS1159 974 of 413.56Up
Larval Salivary gland5 11 of 4 0.06Down
Larval midgut4 11 of 4 0.05Down
Larval tubule3 00 of 4 0.00Down
Larval hindgut9 14 of 4 0.10Down
Larval fat body4 10 of 4 0.10Down
Larval trachea21 244 of 4 0.25Down
Larval carcass13 04 of 4 0.16Down
S2 cells (growing)4 12 of 4 0.06Down
Whole fly85 54 of 4

Looking for CG7727-RA. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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