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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG7892-RE through 18771 annotations produced 1 hits

nemo (nmo):

Annotation Number : CG7892
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0011817
Gbrowse : chr3L:7972148-8043450 (+) // 100.0 //
Probeset : 1624300_s_at
Accessions : protein= NP_523967; /// NP_729316; /// NP_729317; /// NP_729318; /// NP_729319; /// NP_729320;, nucleotide= NM_079243; /// NM_168248; /// NM_168249; /// NM_168250; /// NM_168251; /// NM_168252;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0011817.
BDGP gene expression has embryonic in situ data for nmo: 18 pix of staining in 7 body parts.
Homophila reports that CG7892 is a close match (7e-11) to human gene NTRK2;TRKB (NP_006171), a gene associated with Obesity, hyperphagia, and developmental delay (3).
BioGrid reports that CG7892 interacts with CG9511 CG5680 CG3619 CG3619 CG9885 CG5460 CG5460 CG2275 CG14548 CG11450 CG4444 CG17579 CG17579 CG5123 CG3936 CG3936 CG2248 CG16973 CG4319 CG18492 CG18492 CG18492 CG18492 CG17964 .
TRiP has 4 RNAi stocks for FBgn0011817 available for purchase.
VDRC has 3 RNAi stocks for FBgn0011817 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain560 264 of 4 2.90Up
Head145 34 of 4 0.80Down
Eye86 34 of 4 0.45Down
Thoracicoabdominal ganglion523 284 of 4 2.70Up
Salivary gland136 124 of 4 0.71Down
Crop102 44 of 4 0.50Down
Midgut38 50 of 4 0.20Down
Tubule45 24 of 4 0.20Down
Hindgut67 24 of 4 0.40Down
Heart49 24 of 4 0.25Down
Fat body86 194 of 4 0.45Down
Ovary365 104 of 4 1.90Up
Testis683 254 of 4 3.50Up
Male accessory glands56 24 of 4 0.30Down
Virgin spermatheca86 64 of 4 0.45Down
Mated spermatheca76 74 of 4 0.40Down
Adult carcass60 14 of 4 0.30Down
Larval CNS710 274 of 4 3.68Up
Larval Salivary gland89 74 of 4 0.46Down
Larval midgut48 44 of 4 0.25Down
Larval tubule50 34 of 4 0.30Down
Larval hindgut92 94 of 4 0.48Down
Larval fat body205 474 of 4 1.10None
Larval trachea75 94 of 4 0.39Down
Larval carcass116 154 of 4 0.60Down
S2 cells (growing)109 24 of 4 0.57Down
Whole fly192 134 of 4

Looking for CG7892-RE. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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