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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG7930-RA through 18771 annotations produced 1 hits

troponin C (TpnC73F):

Annotation Number : CG7930
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010424
Gbrowse : chr3L:17039263-17041477 (+) // 100.0 //
Probeset : 1631217_a_at
Accessions : protein= NP_524122; /// NP_730242;, nucleotide= NM_079398; /// NM_168715;
Interpro : 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceabl
FlyMine data for FBgn0010424.
BDGP gene expression has embryonic in situ data for TpnC73F: 11 pix of staining in 2 body parts.
Homophila reports that CG7930 is a close match (5e-13) to human gene CMD1Z;TNNC1 (NP_003271), a gene associated with Cardiomyopathy, dilated, 1Z, 611879 (3);Cardiomyopathy, familial hypertrophic, 192600 (3) (?).
VDRC has 2 RNAi stocks for FBgn0010424 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain23 14 of 4 0.10Down
Head53 54 of 4 0.30Down
Eye7 20 of 4 0.04Down
Thoracicoabdominal ganglion21 43 of 4 0.10Down
Salivary gland41 13 of 4 0.23Down
Crop3414 1124 of 419.20Up
Midgut243 44 of 4 1.40Up
Tubule43 33 of 4 0.20Down
Hindgut2144 304 of 412.10Up
Heart803 764 of 4 4.53Up
Fat body63 224 of 4 0.36Down
Ovary49 44 of 4 0.30Down
Testis51 54 of 4 0.30Down
Male accessory glands438 164 of 4 2.50Up
Virgin spermatheca52 84 of 4 0.30Down
Mated spermatheca88 104 of 4 0.50Down
Adult carcass171 174 of 4 1.00None
Larval CNS44 104 of 4 0.25Down
Larval Salivary gland246 184 of 4 1.39Up
Larval midgut370 284 of 4 2.09Up
Larval tubule51 24 of 4 0.30Down
Larval hindgut3539 574 of 419.94Up
Larval fat body35 54 of 4 0.20Down
Larval trachea368 1884 of 4 2.08None
Larval carcass5444 4094 of 430.68Up
S2 cells (growing)2 10 of 4 0.02Down
Whole fly177 164 of 4

Looking for CG7930-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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