FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for CG8196-RA through 18771 annotations produced 1 hits

Ance-4 (Ance-4):

Annotation Number : CG8196
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0033366
Gbrowse : chr2R:4927224-4929647 (-) // 100.0 //
Probeset : 1641280_at
Accessions : protein= NP_610442;, nucleotide= NM_136598;
Pathway : 0016020 // membrane // inferred from electronic annotation
Interpro : 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity //
FlyMine data for FBgn0033366.
BDGP gene expression has embryonic in situ data for Ance-4: 11 pix of staining in 3 body parts.
Homophila reports that CG8196 is a close match (9e-58) to human gene ACE;ACE1;DCP1 (NP_000780), a gene associated with Renal tubular dysgenesis, 267430 (3);[Angiotensin I-converting enzyme, benign serum increase] (3);{Alzheimer disease, susceptibility to}, 104300 (3);{Diabetic nephropathy, susceptibility to}, 603933 (3);{Myocardial infarction, susceptibility to} (3);{SARS, progression of} (3).
VDRC has 3 RNAi stocks for FBgn0033366 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	23 ± 3	4 of 4	0.10	Down
Head	655 ± 34	4 of 4	3.40	Up
Eye	303 ± 57	4 of 4	1.58	None
Thoracicoabdominal ganglion	31 ± 1	4 of 4	0.20	Down
Salivary gland	8 ± 2	1 of 4	0.04	Down
Crop	19 ± 5	3 of 4	0.10	Down
Midgut	4 ± 1	0 of 4	0.00	Down
Tubule	11 ± 2	2 of 4	0.10	Down
Hindgut	73 ± 10	4 of 4	0.40	Down
Heart	882 ± 30	4 of 4	4.60	Up
Fat body	1809 ± 180	4 of 4	9.44	Up
Ovary	2 ± 0	0 of 4	0.00	Down
Testis	1 ± 0	0 of 4	0.00	Down
Male accessory glands	6 ± 2	1 of 4	0.00	Down
Virgin spermatheca	1937 ± 43	4 of 4	10.10	Up
Mated spermatheca	1979 ± 95	4 of 4	10.33	Up
Adult carcass	968 ± 61	4 of 4	5.10	Up
Larval CNS	4 ± 1	2 of 4	0.02	Down
Larval Salivary gland	74 ± 8	4 of 4	0.39	Down
Larval midgut	17 ± 2	4 of 4	0.09	Down
Larval tubule	13 ± 1	4 of 4	0.10	Down
Larval hindgut	98 ± 17	4 of 4	0.51	Down
Larval fat body	3599 ± 341	4 of 4	18.80	Up
Larval trachea	39 ± 26	4 of 4	0.21	Down
Larval carcass	20 ± 1	4 of 4	0.11	Down
S2 cells (growing)	2 ± 0	0 of 4	0.01	Down
Whole fly	191 ± 12	4 of 4

Looking for CG8196-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720