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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG8721-RA through 18771 annotations produced 1 hits

ornithine decarboxylase (Odc1):

Annotation Number : CG8721
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0013307
Gbrowse : chr2R:3892307-3894178 (+) // 100.0 //
Probeset : 1635318_at
Accessions : protein= NP_477052;, nucleotide= NM_057704;
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004586 // ornithine decarboxylase activity //
FlyMine data for FBgn0013307.
BDGP gene expression has embryonic in situ data for Odc1: 5 pix of staining in 1 body parts.
Homophila reports that CG8721 is a close match (1e-90) to human gene ODC1 (NP_002530), a gene associated with {Colonic adenoma recurrence, reduced risk of}, 114500 (3).
VDRC has 2 RNAi stocks for FBgn0013307 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain13 12 of 4 0.10Down
Head559 574 of 4 2.20Up
Eye255 764 of 4 1.02None
Thoracicoabdominal ganglion18 42 of 4 0.10Down
Salivary gland14 40 of 4 0.06Down
Crop17 21 of 4 0.10Down
Midgut3 00 of 4 0.00Down
Tubule21 102 of 4 0.10Down
Hindgut92 44 of 4 0.40Down
Heart1344 1324 of 4 5.36Up
Fat body2563 1414 of 410.23Up
Ovary1 00 of 4 0.00Down
Testis4 00 of 4 0.00Down
Male accessory glands9 20 of 4 0.00Down
Virgin spermatheca2090 844 of 4 8.34Up
Mated spermatheca2506 844 of 410.00Up
Adult carcass1465 784 of 4 5.80Up
Larval CNS0 00 of 4 0.00Down
Larval Salivary gland10 20 of 4 0.04Down
Larval midgut4 10 of 4 0.02Down
Larval tubule34 34 of 4 0.10Down
Larval hindgut24 22 of 4 0.10Down
Larval fat body2398 2614 of 4 9.60Up
Larval trachea15 61 of 4 0.06Down
Larval carcass10 11 of 4 0.04Down
S2 cells (growing)2 10 of 4 0.01Down
Whole fly250 374 of 4

Looking for CG8721-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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