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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for CG9031-RA through 18771 annotations produced 1 hits

Ras suppressor-1 (ics):

Annotation Number : CG9031
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0028546
Gbrowse : chr2L:13639526-13641271 (-) // 100.0 //
Probeset : 1629423_at
Accessions : protein= NP_609665;, nucleotide= NM_135821;
Interpro : 0005083 // small GTPase regulator activity // inferred from sequence or structural similarity /// 0005515 // protein bin
FlyMine data for FBgn0028546.
BDGP gene expression has embryonic in situ data for BG:BACR48E02.4: 14 pix of staining in 4 body parts.
Homophila reports that CG9031 is a close match (3e-16) to human gene LRRC8;KIAA1437 (NP_062540), a gene associated with Agammaglobulinemia, non-Bruton type, 601495 (3).
BioGrid reports that CG9031 interacts with CG9173 CG9999 .
VDRC has 2 RNAi stocks for FBgn0028546 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain128 24 of 4 0.70Down
Head133 74 of 4 0.70Down
Eye136 84 of 4 0.75Down
Thoracicoabdominal ganglion114 24 of 4 0.60Down
Salivary gland228 154 of 4 1.25None
Crop429 184 of 4 2.30Up
Midgut255 84 of 4 1.40Up
Tubule270 74 of 4 1.50Up
Hindgut321 64 of 4 1.80Up
Heart267 114 of 4 1.46Up
Fat body148 124 of 4 0.81Down
Ovary313 34 of 4 1.70Up
Testis45 14 of 4 0.20Down
Male accessory glands160 154 of 4 0.90None
Virgin spermatheca171 104 of 4 0.93None
Mated spermatheca187 104 of 4 1.03None
Adult carcass188 84 of 4 1.00None
Larval CNS149 84 of 4 0.81Down
Larval Salivary gland527 394 of 4 2.88Up
Larval midgut300 84 of 4 1.64Up
Larval tubule529 84 of 4 2.90Up
Larval hindgut433 64 of 4 2.37Up
Larval fat body224 244 of 4 1.20None
Larval trachea513 134 of 4 2.80Up
Larval carcass686 284 of 4 3.75Up
S2 cells (growing)650 124 of 4 3.55Up
Whole fly183 44 of 4

Looking for CG9031-RA. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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