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FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for CG9761-RA through 18771 annotations produced 1 hits



Neprilysin 2 (Nep2):

Annotation Number : CG9761
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0027570
Gbrowse : chr3R:545518-557595 (-) // 100.0 //
Probeset : 1625075_at
Accessions : protein= NP_524227;, nucleotide= NM_079503;
Interpro : 0004222 // metalloendopeptidase activity // inferred from mutant phenotype /// 0004222 // metalloendopeptidase activity
FlyMine data for FBgn0027570.
BDGP gene expression has embryonic in situ data for Nep2: 14 pix of staining in 8 body parts.
Homophila reports that CG9761 is a close match (5e-47) to human gene KEL (NP_000411), a gene associated with [Blood group, Kell] (3).
VDRC has 3 RNAi stocks for FBgn0027570 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain97 ± 14 of 4 0.80None
Head252 ± 144 of 4 2.10Up
Eye47 ± 74 of 4 0.39Down
Thoracicoabdominal ganglion305 ± 184 of 4 2.50Up
Salivary gland2954 ± 1044 of 424.19Up
Crop95 ± 74 of 4 0.80None
Midgut12 ± 20 of 4 0.10Down
Tubule477 ± 564 of 4 3.90Up
Hindgut208 ± 94 of 4 1.70Up
Heart5 ± 11 of 4 0.04Down
Fat body7 ± 20 of 4 0.06Down
Ovary90 ± 124 of 4 0.70None
Testis71 ± 24 of 4 0.60None
Male accessory glands17 ± 22 of 4 0.10Down
Virgin spermatheca1341 ± 654 of 410.99Up
Mated spermatheca1736 ± 1624 of 414.22Up
Adult carcass113 ± 104 of 4 0.90None
Larval CNS14 ± 24 of 4 0.12Down
Larval Salivary gland179 ± 164 of 4 1.47None
Larval midgut24 ± 24 of 4 0.20Down
Larval tubule507 ± 234 of 4 4.20Up
Larval hindgut552 ± 444 of 4 4.53Up
Larval fat body144 ± 154 of 4 1.20None
Larval trachea65 ± 154 of 4 0.54None
Larval carcass896 ± 2644 of 4 7.34None
S2 cells (growing)2 ± 00 of 4 0.02Down
Whole fly122 ± 224 of 4

Looking for CG9761-RA. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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