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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0000108 through 18771 annotations produced 1 hits



beta-amyloid-protein-precursor-like (Appl):

Annotation Number : CG7727
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000108
Gbrowse : chrX:425651-472163 (+) // 99.83 //
Probeset : 1624033_at
Accessions : protein= NP_476626;, nucleotide= NM_057278;
Pathway : 0005576 // extracellular region // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct ass
Interpro : 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical inter
FlyMine data for FBgn0000108.
BDGP gene expression has embryonic in situ data for Appl: 9 pix of staining in 4 body parts.
Homophila reports that CG7727 is a close match (3e-27) to human gene AAA;AD1;APP;CVAP (NP_958817), a gene associated with Alzheimer disease-1, APP-related (3);Amyloidosis, cerebroarterial, Dutch type (3);Amyloidosis, cerebroarterial, Iowa type, 605714 (3).
BioGrid reports that CG7727 interacts with CG7765 CG7765 CG5433 CG17299 CG12348 CG12348 CG10751 CG1200 CG1200 .
TRiP has 2 RNAi stocks for FBgn0000108 available for purchase.
VDRC has 3 RNAi stocks for FBgn0000108 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1555 ± 554 of 418.20Up
Head632 ± 544 of 4 7.40Up
Eye690 ± 664 of 4 8.07Up
Thoracicoabdominal ganglion1273 ± 464 of 414.90Up
Salivary gland12 ± 12 of 4 0.14Down
Crop7 ± 11 of 4 0.10Down
Midgut7 ± 11 of 4 0.10Down
Tubule6 ± 01 of 4 0.10Down
Hindgut7 ± 23 of 4 0.10Down
Heart9 ± 04 of 4 0.11Down
Fat body14 ± 84 of 4 0.17Down
Ovary3 ± 00 of 4 0.00Down
Testis2 ± 01 of 4 0.00Down
Male accessory glands6 ± 00 of 4 0.10Down
Virgin spermatheca13 ± 13 of 4 0.16Down
Mated spermatheca17 ± 53 of 4 0.20Down
Adult carcass39 ± 84 of 4 0.50Down
Larval CNS1159 ± 974 of 413.56Up
Larval Salivary gland5 ± 11 of 4 0.06Down
Larval midgut4 ± 11 of 4 0.05Down
Larval tubule3 ± 00 of 4 0.00Down
Larval hindgut9 ± 14 of 4 0.10Down
Larval fat body4 ± 10 of 4 0.10Down
Larval trachea21 ± 244 of 4 0.25Down
Larval carcass13 ± 04 of 4 0.16Down
S2 cells (growing)4 ± 12 of 4 0.06Down
Whole fly85 ± 54 of 4

Looking for FBgn0000108. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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