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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0000320 through 18771 annotations produced 1 hits

clift (eya):

Annotation Number : CG9554
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000320
Gbrowse : chr2L:6527448-6546972 (-) // 100.0 //
Probeset : 1623206_a_at
Accessions : protein= NP_523492; /// NP_723188;, nucleotide= NM_078768; /// NM_164693;
Pathway : 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005634 //
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity
FlyMine data for FBgn0000320.
BDGP gene expression has embryonic in situ data for eya: 38 pix of staining in 20 body parts.
Homophila reports that CG9554 is a close match (1e-88) to human gene EYA1;BOR (NP_742056), a gene associated with Anterior segment anomalies and cataract (3);Branchiootic syndrome (3);Branchiootorenal syndrome with cataract, 113650 (3);Branchiootorenal syndrome, 113650 (3);Otofaciocervical syndrome, 166780 (3).
BioGrid reports that CG9554 interacts with CG3166 CG10079 CG12399 CG9375 CG9375 CG4952 CG4952 CG4952 CG4952 CG4952 CG4952 CG9885 CG9885 CG1464 CG1464 CG1464 CG1464 CG1464 CG1464 CG1464 CG1464 CG2845 CG12559 CG12559 CG11121 CG11121 CG11121 CG11121 CG11121 CG11121 CG11121 CG11121 CG11121 CG11121 CG1374 .
TRiP has 2 RNAi stocks for FBgn0000320 available for purchase.
VDRC has 2 RNAi stocks for FBgn0000320 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain19 24 of 4 0.50Down
Head153 64 of 4 4.40Up
Eye325 34 of 4 9.30Up
Thoracicoabdominal ganglion9 13 of 4 0.30Down
Salivary gland6 10 of 4 0.19Down
Crop1 00 of 4 0.00Down
Midgut2 10 of 4 0.10Down
Tubule4 10 of 4 0.10Down
Hindgut1 00 of 4 0.00Down
Heart2 00 of 4 0.07Down
Fat body6 33 of 4 0.20Down
Ovary44 24 of 4 1.30None
Testis89 94 of 4 2.60Up
Male accessory glands0 00 of 4 0.00Down
Virgin spermatheca1 00 of 4 0.03Down
Mated spermatheca2 10 of 4 0.07Down
Adult carcass14 13 of 4 0.40Down
Larval CNS135 284 of 4 3.86Up
Larval Salivary gland3 10 of 4 0.10Down
Larval midgut4 21 of 4 0.12Down
Larval tubule8 13 of 4 0.20Down
Larval hindgut2 11 of 4 0.08Down
Larval fat body33 24 of 4 1.00None
Larval trachea8 44 of 4 0.25Down
Larval carcass9 04 of 4 0.28Down
S2 cells (growing)1 00 of 4 0.05Down
Whole fly35 34 of 4

Looking for FBgn0000320. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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