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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0000346 through 18771 annotations produced 1 hits

N-ethylmaleimide-sensitive fusion protein (comt):

Annotation Number : CG1618
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000346
Gbrowse : chrX:13153027-13156527 (+) // 100.0 //
Probeset : 1639825_at
Accessions : protein= NP_524877;, nucleotide= NM_080138;
Pathway : engulfment // inferred from mutant phenotype /// 0007030 // Golgi organization // inferred from mutant phenotype /// 00
Interpro : 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // non-traceable author
FlyMine data for FBgn0000346.
BDGP gene expression has embryonic in situ data for comt: 18 pix of staining in 11 body parts.
Homophila reports that CG1618 is a close match (2e-13) to human gene CAR;CMAR;PGN;SPG7 (NP_955399), a gene associated with Spastic paraplegia-7, 607259 (3).
BioGrid reports that CG1618 interacts with CG33520 CG1522 CG18102 CG33101 .
TRiP has 3 RNAi stocks for FBgn0000346 available for purchase.
VDRC has 2 RNAi stocks for FBgn0000346 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1938 244 of 412.30Up
Head1030 364 of 4 6.60Up
Eye1466 664 of 4 9.34Up
Thoracicoabdominal ganglion2863 664 of 418.20Up
Salivary gland8 40 of 4 0.06Down
Crop20 14 of 4 0.10Down
Midgut4 10 of 4 0.00Down
Tubule4 00 of 4 0.00Down
Hindgut12 20 of 4 0.10Down
Heart8 12 of 4 0.06Down
Fat body7 30 of 4 0.04Down
Ovary117 44 of 4 0.70Down
Testis261 54 of 4 1.70Up
Male accessory glands4 10 of 4 0.00Down
Virgin spermatheca3 10 of 4 0.02Down
Mated spermatheca7 20 of 4 0.05Down
Adult carcass70 44 of 4 0.40Down
Larval CNS614 284 of 4 3.91Up
Larval Salivary gland2 00 of 4 0.01Down
Larval midgut6 10 of 4 0.04Down
Larval tubule1 00 of 4 0.00Down
Larval hindgut7 10 of 4 0.05Down
Larval fat body60 293 of 4 0.40Down
Larval trachea35 364 of 4 0.22Down
Larval carcass18 11 of 4 0.12Down
S2 cells (growing)2 10 of 4 0.02Down
Whole fly156 84 of 4

Looking for FBgn0000346. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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