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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0000405 through 18771 annotations produced 1 hits

chr2R:18691026-18694490 (-) // 100.0 // (Cyclin B):

Annotation Number : CG3510
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : full length
Gbrowse : March 2006 (FlyBase/BDGP 5.3)
Probeset : 1639876_a_at
Accessions : protein= , nucleotide= NP_726244; /// NP_726245; /// NP_726246; /// NP_726247;
Pathway : 0000086 // G2/M transition of mitotic cell cycle // non-traceable author statement /// 0000092 // mitotic anaphase B //
Interpro : "0000775 // chromosome
FlyMine data for full length.
Homophila reports that CG3510 is a close match (3e-12) to human gene BCL1;CCND1;PRAD1 (NP_444284), a gene associated with Centrocytic lymphoma (2);Leukemia/lymphoma, chronic B-cell, 151400 (3);Multiple myeloma, 254500 (2);Parathyroid adenomatosis 1 (2);von Hippel-Lindau disease, modification of, 193300 (3);{Colorectal cancer, susceptibility to} (3).
BioGrid reports that CG3510 interacts with CG3668 CG4758 CG5099 CG6945 CG7763 CG7838 CG8368 CG9117 CG9415 CG9465 CG9654 CG9553 CG5940 CG5940 CG5940 CG5940 CG5940 CG5940 CG5940 CG5940 CG5940 CG5940 CG5940 CG5940 CG6174 CG12530 CG7507 CG9206 CG9045 CG9045 CG5363 CG5363 CG5363 CG5363 CG5363 CG5363 CG1768 CG1768 CG5272 CG4252 CG3060 CG9183 CG11420 CG11420 CG6433 CG10751 CG4336 CG3273 CG3595 CG15792 CG32169 .

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain6 11 of 4 0.00Down
Head7 11 of 4 0.00Down
Eye9 11 of 4 0.01Down
Thoracicoabdominal ganglion8 03 of 4 0.00Down
Salivary gland35 23 of 4 0.02Down
Crop30 54 of 4 0.00Down
Midgut23 34 of 4 0.00Down
Tubule71 573 of 4 0.00Down
Hindgut23 24 of 4 0.00Down
Heart9 00 of 4 0.01Down
Fat body55 424 of 4 0.03Down
Ovary2919 554 of 4 1.60Up
Testis56 64 of 4 0.00Down
Male accessory glands8 22 of 4 0.00Down
Virgin spermatheca64 94 of 4 0.04Down
Mated spermatheca30 114 of 4 0.02Down
Adult carcass114 454 of 4 0.10Down
Larval CNS795 1094 of 4 0.45Down
Larval Salivary gland11 12 of 4 0.01Down
Larval midgut49 64 of 4 0.03Down
Larval tubule15 12 of 4 0.00Down
Larval hindgut38 34 of 4 0.02Down
Larval fat body45 34 of 4 0.00Down
Larval trachea109 134 of 4 0.06Down
Larval carcass80 54 of 4 0.04Down
S2 cells (growing)601 174 of 4 0.34Down
Whole fly1779 494 of 4

Looking for FBgn0000405. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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