FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0000546 through 18771 annotations produced 1 hits

ecdysone receptor (EcR):

Annotation Number : CG1765
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000546
Gbrowse : chr2R:1978284-2056589 (-) // 100.0 //
Probeset : 1632796_s_at
Accessions : protein= NP_001163061; /// NP_724456; /// NP_724457; /// NP_724458; /// NP_724459; /// NP_724460;, nucleotide= NM_001169590; /// NM_165461; /// NM_165462; /// NM_165463; /// NM_165464; /// NM_165465;
Pathway : DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II
Interpro : chitin-based cuticle // inferred from mutant phenotype /// 0035053 // dorsal vessel heart proper cell fate commitment /
FlyMine data for FBgn0000546.
BDGP gene expression has embryonic in situ data for EcR: 5 pix of staining in 1 body parts.
Homophila reports that CG1765 is a close match (3e-14) to human gene AR;DHTR;KD;SBMA;SMAX1;TFM (NP_000035), a gene associated with Androgen insensitivity, 300068 (3);Breast cancer, male, with Reifenstein syndrome (3);Hypospadias, perineal, 300633 (3);Prostate cancer (3);Spinal and bulbar muscular atrophy of Kennedy, 313200 (3);{Prostate cancer, susceptibility to}, 176807 (3).
BioGrid reports that CG1765 interacts with CG9456 CG2189 CG8224 CG9623 CG1560 CG30149 CG3848 CG3848 EG9318 .
TRiP has 1 RNAi stocks for FBgn0000546 available for purchase.
VDRC has 2 RNAi stocks for FBgn0000546 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	57 ± 1	4 of 4	2.30	Up
Head	29 ± 1	4 of 4	1.20	None
Eye	26 ± 2	4 of 4	1.09	None
Thoracicoabdominal ganglion	35 ± 4	4 of 4	1.40	None
Salivary gland	44 ± 7	4 of 4	1.80	None
Crop	44 ± 3	4 of 4	1.80	Up
Midgut	19 ± 2	4 of 4	0.80	None
Tubule	25 ± 1	4 of 4	1.00	None
Hindgut	33 ± 2	4 of 4	1.40	Up
Heart	23 ± 1	4 of 4	0.95	None
Fat body	103 ± 4	4 of 4	4.18	Up
Ovary	49 ± 2	4 of 4	2.00	Up
Testis	6 ± 1	4 of 4	0.30	Down
Male accessory glands	27 ± 1	4 of 4	1.10	None
Virgin spermatheca	67 ± 11	4 of 4	2.71	Up
Mated spermatheca	74 ± 7	4 of 4	2.98	Up
Adult carcass	32 ± 4	4 of 4	1.30	None
Larval CNS	163 ± 31	4 of 4	6.58	Up
Larval Salivary gland	460 ± 122	4 of 4	18.56	Up
Larval midgut	236 ± 57	4 of 4	9.53	Up
Larval tubule	162 ± 16	4 of 4	6.60	Up
Larval hindgut	325 ± 34	4 of 4	13.11	Up
Larval fat body	188 ± 8	4 of 4	7.60	Up
Larval trachea	143 ± 16	4 of 4	5.78	Up
Larval carcass	313 ± 14	4 of 4	12.62	Up
S2 cells (growing)	43 ± 5	4 of 4	1.76	Up
Whole fly	24 ± 1	4 of 4

Looking for FBgn0000546. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720