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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0000547 through 18771 annotations produced 1 hits

echinoid (ed):

Annotation Number : CG12676
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000547
Gbrowse : chr2L:4031378-4115059 (+) // 100.0 //
Probeset : 1627506_at
Accessions : protein= NP_523469;, nucleotide= NM_078745;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from dir
Interpro : 0005515 // protein binding // inferred from physical interaction
FlyMine data for FBgn0000547.
BDGP gene expression has embryonic in situ data for ed: 32 pix of staining in 23 body parts.
Homophila reports that CG12676 is a close match (3e-11) to human gene FGFR1;FLT2;KAL2 (NP_075594), a gene associated with Jackson-Weiss syndrome, 123150 (3);Kallmann syndrome 2, 147950 (3);Pfeiffer syndrome, 101600 (3).
BioGrid reports that CG12676 interacts with CG13467 CG15803 CG15525 CG6416 CG7809 CG3166 CG10079 CG1634 CG1634 CG9375 CG9375 CG4531 CG12283 CG17077 CG1004 CG12559 CG9949 CG1921 CG1921 CG31774 .
TRiP has 2 RNAi stocks for FBgn0000547 available for purchase.
VDRC has 5 RNAi stocks for FBgn0000547 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain36 34 of 4 0.80Down
Head34 44 of 4 0.80None
Eye45 64 of 4 1.00None
Thoracicoabdominal ganglion21 14 of 4 0.50Down
Salivary gland45 83 of 4 1.01None
Crop184 94 of 4 4.10Up
Midgut9 10 of 4 0.20Down
Tubule13 02 of 4 0.30Down
Hindgut39 34 of 4 0.90None
Heart16 14 of 4 0.37Down
Fat body16 34 of 4 0.36Down
Ovary172 64 of 4 3.80Up
Testis13 13 of 4 0.30Down
Male accessory glands83 74 of 4 1.90Up
Virgin spermatheca9 03 of 4 0.20Down
Mated spermatheca8 23 of 4 0.18Down
Adult carcass41 44 of 4 0.90None
Larval CNS111 154 of 4 2.48Up
Larval Salivary gland88 64 of 4 1.95Up
Larval midgut14 12 of 4 0.31Down
Larval tubule28 34 of 4 0.60Down
Larval hindgut49 34 of 4 1.09None
Larval fat body3 10 of 4 0.10Down
Larval trachea145 134 of 4 3.24Up
Larval carcass46 44 of 4 1.04None
S2 cells (growing)8 10 of 4 0.20Down
Whole fly45 24 of 4

Looking for FBgn0000547. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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