FlyAtlas: the Drosophila gene expression atlas

Biotechnology & Biological Sciences Research Council

Home & Search

Batch/table Search

Tissues Search

BLASTP Search

About & FAQ

Top 50

Original data

Interesting meta-analysis

Links

Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0000559 through 18771 annotations produced 1 hits

Elongation factor 2b (Ef2b):

Annotation Number : CG2238
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000559
Gbrowse : chr2L:21678096-21682150 (-) // 100.0 //
Probeset : 1625150_s_at
Accessions : protein= NP_525105; /// NP_724357; /// NP_724358;, nucleotide= NM_080366; /// NM_165394; /// NM_165395;
Pathway : 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activi
FlyMine data for FBgn0000559.
BDGP gene expression has embryonic in situ data for Ef2b: 4 pix of staining in 2 body parts.
Homophila reports that CG2238 is a close match (4e-24) to human gene COXPD1;EFG1;GFM;GFM1 (NP_079272), a gene associated with Combined oxidative phosphorylation deficiency 1, 609060 (3).
BioGrid reports that CG2238 interacts with CG9170 CG2540 CG2835 CG3225 CG33017 CG3758 CG3918 CG3966 CG4877 CG5258 CG5576 CG6378 CG7098 CG8316 CG8427 CG8786 CG8942 CG9163 Dmel CG14425 CG5829 .
VDRC has 1 RNAi stocks for FBgn0000559 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	2796 ± 82	4 of 4	0.70	Down
Head	4261 ± 82	4 of 4	1.10	None
Eye	5758 ± 49	4 of 4	1.46	Up
Thoracicoabdominal ganglion	4229 ± 140	4 of 4	1.10	None
Salivary gland	13984 ± 522	4 of 4	3.55	Up
Crop	5850 ± 382	4 of 4	1.50	Up
Midgut	4620 ± 103	4 of 4	1.20	None
Tubule	6217 ± 55	4 of 4	1.60	Up
Hindgut	4798 ± 115	4 of 4	1.20	Up
Heart	5730 ± 314	4 of 4	1.46	Up
Fat body	5097 ± 591	4 of 4	1.29	Up
Ovary	3193 ± 55	4 of 4	0.80	None
Testis	1442 ± 18	4 of 4	0.40	Down
Male accessory glands	9555 ± 296	4 of 4	2.40	Up
Virgin spermatheca	5165 ± 208	4 of 4	1.31	Up
Mated spermatheca	5308 ± 240	4 of 4	1.35	Up
Adult carcass	5706 ± 312	4 of 4	1.40	Up
Larval CNS	2467 ± 149	4 of 4	0.63	Down
Larval Salivary gland	6694 ± 438	4 of 4	1.70	Up
Larval midgut	4652 ± 115	4 of 4	1.18	None
Larval tubule	5413 ± 106	4 of 4	1.40	Up
Larval hindgut	4247 ± 45	4 of 4	1.08	None
Larval fat body	7034 ± 741	4 of 4	1.80	Up
Larval trachea	5555 ± 335	4 of 4	1.41	Up
Larval carcass	4600 ± 335	4 of 4	1.17	None
S2 cells (growing)	4345 ± 123	4 of 4	1.10	None
Whole fly	3938 ± 256	4 of 4

Looking for FBgn0000559. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720