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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0000592 through 18771 annotations produced 1 hits



Esterase-6 (Est-6):

Annotation Number : CG6917
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0000592
Gbrowse : chr3L:12181934-12183681 (+) // 100.0 //
Probeset : 1631224_at
Accessions : protein= NP_788500;, nucleotide= NM_176322;
Pathway : post-mating // traceable author statement /// 0046662 // regulation of oviposition // traceable author statement /// 00
Interpro : 0005576 // extracellular region // inferred from electronic annotation
FlyMine data for FBgn0000592.
BDGP gene expression has embryonic in situ data for Est-6: 21 pix of staining in 3 body parts.
Homophila reports that CG6917 is a close match (5e-25) to human gene AITD3;TG (NP_003226), a gene associated with Goiter, adolescent multinodular (1);Goiter, nonendemic, simple (3);Hypothyroidism, hereditary congenital (3);{Autoimmune thyroid disease, susceptibility to 3}, 608175 (3).
VDRC has 2 RNAi stocks for FBgn0000592 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain130 ± 104 of 4 0.10Down
Head2367 ± 1354 of 4 1.60Up
Eye823 ± 1894 of 4 0.56None
Thoracicoabdominal ganglion177 ± 464 of 4 0.10Down
Salivary gland15630 ± 7134 of 410.64Up
Crop508 ± 644 of 4 0.30Down
Midgut3 ± 11 of 4 0.00Down
Tubule49 ± 193 of 4 0.00Down
Hindgut141 ± 194 of 4 0.10Down
Heart2006 ± 1594 of 4 1.37None
Fat body2194 ± 1924 of 4 1.49None
Ovary3 ± 01 of 4 0.00Down
Testis121 ± 174 of 4 0.10Down
Male accessory glands2568 ± 4914 of 4 1.70None
Virgin spermatheca1823 ± 454 of 4 1.24None
Mated spermatheca2140 ± 714 of 4 1.46None
Adult carcass1976 ± 1044 of 4 1.30None
Larval CNS2 ± 22 of 4 0.00Down
Larval Salivary gland9 ± 13 of 4 0.01Down
Larval midgut9 ± 12 of 4 0.01Down
Larval tubule2 ± 10 of 4 0.00Down
Larval hindgut5 ± 10 of 4 0.00Down
Larval fat body29 ± 34 of 4 0.00Down
Larval trachea15 ± 154 of 4 0.01Down
Larval carcass7 ± 03 of 4 0.00Down
S2 cells (growing)2 ± 11 of 4 0.00Down
Whole fly1468 ± 2524 of 4

Looking for FBgn0000592. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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