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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0000659 through 18771 annotations produced 1 hits

chr3R:24407537-24410805 (-) // 100.0 // (Fork Head):

Annotation Number : CG10002
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : full length
Gbrowse : March 2006 (FlyBase/BDGP 5.3)
Probeset : 1630305_at
Accessions : protein= , nucleotide= NP_001163762; /// NP_524542;
Pathway : "0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 00017
Interpro : DNA-dependent // inferred from sequence or structural similarity /// 0006355 // regulation of transcription
FlyMine data for full length.
Homophila reports that CG10002 is a close match (9e-11) to human gene FOXN1;WHN (NP_003584), a gene associated with T-cell immunodeficiency, congenital alopecia, and nail dystrophy, 601705 (3).
BioGrid reports that CG10002 interacts with CG6459 CG10032 CG11899 CG15224 CG15529 CG41099 CG17666 CG17945 CG17946 CG1925 Dmel CG34168 CG6238 CG7081 CG9572 CG31054 CG4849 CG7260 .

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain75 14 of 4 2.10Up
Head25 43 of 4 0.70None
Eye4 00 of 4 0.14Down
Thoracicoabdominal ganglion17 14 of 4 0.50Down
Salivary gland804 994 of 422.63Up
Crop477 154 of 413.40Up
Midgut105 34 of 4 3.00Up
Tubule143 124 of 4 4.00Up
Hindgut452 54 of 412.70Up
Heart2 10 of 4 0.06Down
Fat body11 40 of 4 0.31Down
Ovary3 00 of 4 0.10Down
Testis1 00 of 4 0.00Down
Male accessory glands9 10 of 4 0.30Down
Virgin spermatheca9 00 of 4 0.25Down
Mated spermatheca12 41 of 4 0.36Down
Adult carcass10 20 of 4 0.30Down
Larval CNS57 24 of 4 1.61Up
Larval Salivary gland515 94 of 414.50Up
Larval midgut35 34 of 4 0.99None
Larval tubule684 384 of 419.20Up
Larval hindgut315 134 of 4 8.87Up
Larval fat body8 20 of 4 0.20Down
Larval trachea1 10 of 4 0.05Down
Larval carcass7 00 of 4 0.21Down
S2 cells (growing)1 00 of 4 0.05Down
Whole fly35 34 of 4

Looking for FBgn0000659. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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