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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0001226 through 18771 annotations produced 1 hits

heat shock protein hsp27 (Hsp27):

Annotation Number : CG4466
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0001226
Gbrowse : chr3L:9377164-9378384 (+) // 100.0 //
Probeset : 1628117_at
Accessions : protein= NP_524000;, nucleotide= NM_079276;
Pathway : 0005875 // microtubule associated complex // inferred from direct assay
Interpro : 0005515 // protein binding // inferred from physical interaction
FlyMine data for FBgn0001226.
BDGP gene expression has embryonic in situ data for Hsp27: 49 pix of staining in 15 body parts.
Homophila reports that CG4466 is a close match (8e-11) to human gene CRYA1;CRYAA (NP_000385), a gene associated with Cataract, autosomal dominant nuclear (3);Cataract, congenital, autosomal recessive (3);Cataract, zonular central nuclear, autosomal dominant (3).
BioGrid reports that CG4466 interacts with CG5546 CG7285 CG8155 CG8440 CG9242 CG9638 CG4354 .
TRiP has 2 RNAi stocks for FBgn0001226 available for purchase.
VDRC has 2 RNAi stocks for FBgn0001226 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain43 24 of 4 0.00Down
Head33 34 of 4 0.00Down
Eye36 34 of 4 0.03Down
Thoracicoabdominal ganglion74 24 of 4 0.10Down
Salivary gland28 33 of 4 0.02Down
Crop93 154 of 4 0.10Down
Midgut39 24 of 4 0.00Down
Tubule1658 4584 of 4 1.30None
Hindgut15 14 of 4 0.00Down
Heart58 74 of 4 0.04Down
Fat body47 44 of 4 0.04Down
Ovary2121 214 of 4 1.60Up
Testis1075 154 of 4 0.80None
Male accessory glands27 53 of 4 0.00Down
Virgin spermatheca90 94 of 4 0.07Down
Mated spermatheca396 1594 of 4 0.30Down
Adult carcass58 204 of 4 0.00Down
Larval CNS2217 2034 of 4 1.68Up
Larval Salivary gland1743 3434 of 4 1.32None
Larval midgut171 604 of 4 0.13Down
Larval tubule3264 1904 of 4 2.50Up
Larval hindgut424 844 of 4 0.32Down
Larval fat body3988 4094 of 4 3.00Up
Larval trachea939 1974 of 4 0.71Down
Larval carcass1079 2964 of 4 0.82None
S2 cells (growing)288 184 of 4 0.22Down
Whole fly1323 974 of 4

Looking for FBgn0001226. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

measure downtime