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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0001258 through 18771 annotations produced 1 hits

lactic DH (ImpL3):

Annotation Number : CG10160
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0001258
Gbrowse : chr3L:6252588-6255793 (-) // 100.0 //
Probeset : 1635227_at
Accessions : protein= NP_476581;, nucleotide= NM_057233;
Pathway : 0005737 // cytoplasm // inferred from electronic annotation
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity //
FlyMine data for FBgn0001258.
BDGP gene expression has embryonic in situ data for ImpL3: 34 pix of staining in 8 body parts.
Homophila reports that CG10160 is a close match (8e-111) to human gene LDH1;LDHA (NP_005557), a gene associated with Exertional myoglobinuria due to deficiency of LDH-A (3).
BioGrid reports that CG10160 interacts with CG17029 CG11327 CG11769 CG13510 CG7357 .
TRiP has 1 RNAi stocks for FBgn0001258 available for purchase.
VDRC has 2 RNAi stocks for FBgn0001258 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain25 10 of 4 0.30Down
Head60 74 of 4 0.80None
Eye13 22 of 4 0.18Down
Thoracicoabdominal ganglion14 20 of 4 0.20Down
Salivary gland138 142 of 4 1.81Up
Crop375 284 of 4 4.90Up
Midgut872 434 of 411.40Up
Tubule33 91 of 4 0.40Down
Hindgut281 214 of 4 3.70Up
Heart375 654 of 4 4.90Up
Fat body435 234 of 4 5.69Up
Ovary1 10 of 4 0.00Down
Testis118 24 of 4 1.50Up
Male accessory glands28 40 of 4 0.40Down
Virgin spermatheca600 544 of 4 7.85Up
Mated spermatheca370 324 of 4 4.84Up
Adult carcass183 114 of 4 2.40Up
Larval CNS1180 2144 of 415.43Up
Larval Salivary gland96 160 of 4 1.26None
Larval midgut115 244 of 4 1.51None
Larval tubule73 74 of 4 1.00None
Larval hindgut594 634 of 4 7.76Up
Larval fat body3 00 of 4 0.00Down
Larval trachea291 1614 of 4 3.80None
Larval carcass4283 3804 of 455.97Up
S2 cells (growing)663 104 of 4 8.67Up
Whole fly76 134 of 4

Looking for FBgn0001258. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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