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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0001269 through 18771 annotations produced 1 hits

invected (inv):

Annotation Number : CG17835
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0001269
Gbrowse : chr2R:7361969-7394688 (+) // 100.0 //
Probeset : 1623909_s_at
Accessions : protein= NP_523699; /// NP_725055; /// NP_725056; /// NP_725057;, nucleotide= NM_078975; /// NM_165837; /// NM_165838; /// NM_165839;
Pathway : DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II
Interpro : 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author sta
FlyMine data for FBgn0001269.
BDGP gene expression has embryonic in situ data for inv: 40 pix of staining in 16 body parts.
Homophila reports that CG17835 is a close match (5e-11) to human gene EMX2 (NP_004089), a gene associated with Schizencephaly, 269160 (3).
BioGrid reports that CG17835 interacts with CG1868 CG3099 CG8384 CG9640 CG2677 CG2934 CG30417 CG32130 CG33017 CG4439 CG5009 CG6905 CG6930 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG9015 CG3388 CG3895 .
TRiP has 1 RNAi stocks for FBgn0001269 available for purchase.
VDRC has 2 RNAi stocks for FBgn0001269 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain7 01 of 4 0.70None
Head9 13 of 4 0.90None
Eye14 04 of 4 1.37None
Thoracicoabdominal ganglion9 00 of 4 0.90None
Salivary gland4 10 of 4 0.43Down
Crop3 00 of 4 0.40Down
Midgut2 00 of 4 0.20Down
Tubule2 00 of 4 0.30Down
Hindgut1 00 of 4 0.20Down
Heart3 10 of 4 0.35Down
Fat body2 10 of 4 0.24Down
Ovary1 00 of 4 0.10Down
Testis37 24 of 4 3.60Up
Male accessory glands0 00 of 4 0.10Down
Virgin spermatheca1 00 of 4 0.11Down
Mated spermatheca3 10 of 4 0.35Down
Adult carcass7 10 of 4 0.70None
Larval CNS15 44 of 4 1.47None
Larval Salivary gland4 10 of 4 0.42Down
Larval midgut7 10 of 4 0.77None
Larval tubule1 00 of 4 0.10Down
Larval hindgut73 74 of 4 7.18Up
Larval fat body7 21 of 4 0.80None
Larval trachea5 41 of 4 0.56None
Larval carcass14 13 of 4 1.42None
S2 cells (growing)1 00 of 4 0.10Down
Whole fly10 12 of 4

Looking for FBgn0001269. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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