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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0002023 through 18771 annotations produced 1 hits

lethal(2)37Bd (Lim3):

Annotation Number : CG10699
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0002023
Gbrowse : chr2L:19079233-19108108 (-) // 100.0 //
Probeset : 1625108_a_at
Accessions : protein= NP_476606; /// NP_724161;, nucleotide= NM_057258; /// NM_165277;
Pathway : DNA-dependent // inferred from sequence or structural similarity /// 0006355 // regulation of transcription
Interpro : DNA-dependent // inferred from electronic annotation /// 0007399 // nervous system development // traceable author stat
FlyMine data for FBgn0002023.
BDGP gene expression has embryonic in situ data for Lim3: 16 pix of staining in 7 body parts.
Homophila reports that CG10699 is a close match (2e-12) to human gene CYPHER;KIAA01613;LDB3;ZASP (NP_009009), a gene associated with Cardiomyopathy, dilated (3);Cardiomyopathy, dilated, with left ventricular noncompaction (3);Myopathy, myofibrillar, ZASP-related, 609452 (3).
BioGrid reports that CG10699 interacts with CG1119 CG18371 CG3924 CG6203 CG6801 CG6972 CG8461 CG8524 CG12496 CG13338 CG13780 CG3052 CG32171 CG3644 CG4735 CG5093 CG6958 CG8813 CG8376 CG33297 Dmel CG13383 .
TRiP has 2 RNAi stocks for FBgn0002023 available for purchase.
VDRC has 3 RNAi stocks for FBgn0002023 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain89 34 of 4 5.50Up
Head12 14 of 4 0.70Down
Eye5 12 of 4 0.36Down
Thoracicoabdominal ganglion64 34 of 4 3.90Up
Salivary gland6 20 of 4 0.39Down
Crop4 10 of 4 0.20Down
Midgut49 14 of 4 3.10Up
Tubule20 24 of 4 1.20None
Hindgut2 10 of 4 0.10Down
Heart3 11 of 4 0.23Down
Fat body7 32 of 4 0.49Down
Ovary2 00 of 4 0.10Down
Testis112 84 of 4 6.90Up
Male accessory glands5 00 of 4 0.30Down
Virgin spermatheca2 00 of 4 0.15Down
Mated spermatheca3 10 of 4 0.19Down
Adult carcass4 20 of 4 0.30Down
Larval CNS135 264 of 4 8.31Up
Larval Salivary gland3 00 of 4 0.21Down
Larval midgut68 64 of 4 4.16Up
Larval tubule17 14 of 4 1.10None
Larval hindgut1 00 of 4 0.10Down
Larval fat body38 182 of 4 2.40None
Larval trachea2 10 of 4 0.14Down
Larval carcass4 00 of 4 0.25Down
S2 cells (growing)1 00 of 4 0.09Down
Whole fly16 04 of 4

Looking for FBgn0002023. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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