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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0002524 through 18771 annotations produced 1 hits

Serine palmitoyltransferase subunit II (lace):

Annotation Number : CG4162
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0002524
Gbrowse : chr2L:15499109-15504598 (+) // 100.0 //
Probeset : 1626368_at
Accessions : protein= NP_476614;, nucleotide= NM_057266;
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0004758 // serine C-palmitoyltransferase activ
FlyMine data for FBgn0002524.
BDGP gene expression has embryonic in situ data for lace: 13 pix of staining in 4 body parts.
Homophila reports that CG4162 is a close match (5e-32) to human gene ALAS2;ANH1;ASB (NP_001033058), a gene associated with Anemia, sideroblastic, X-linked, 300751 (3).
BioGrid reports that CG4162 interacts with CG5802 CG6126 CG4193 CG4264 CG4287 CG5271 CG6213 CG6453 CG9986 CG5460 CG8946 .
VDRC has 3 RNAi stocks for FBgn0002524 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain213 74 of 4 0.80Down
Head152 54 of 4 0.60Down
Eye101 24 of 4 0.39Down
Thoracicoabdominal ganglion341 154 of 4 1.30Up
Salivary gland510 84 of 4 1.97Up
Crop281 174 of 4 1.10None
Midgut493 144 of 4 1.90Up
Tubule309 114 of 4 1.20Up
Hindgut347 44 of 4 1.30Up
Heart257 104 of 4 0.99None
Fat body148 254 of 4 0.57Down
Ovary623 74 of 4 2.40Up
Testis57 24 of 4 0.20Down
Male accessory glands187 34 of 4 0.70Down
Virgin spermatheca201 154 of 4 0.78Down
Mated spermatheca247 184 of 4 0.95None
Adult carcass114 54 of 4 0.40Down
Larval CNS402 194 of 4 1.55Up
Larval Salivary gland135 84 of 4 0.52Down
Larval midgut1009 944 of 4 3.89Up
Larval tubule421 404 of 4 1.60Up
Larval hindgut1375 404 of 4 5.30Up
Larval fat body269 164 of 4 1.00None
Larval trachea347 214 of 4 1.34Up
Larval carcass313 164 of 4 1.21Up
S2 cells (growing)1804 364 of 4 6.95Up
Whole fly259 64 of 4

Looking for FBgn0002524. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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