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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0002526 through 18771 annotations produced 1 hits

Laminin (LanA):

Annotation Number : CG10236
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0002526
Gbrowse : chr3L:6196930-6211084 (-) // 100.0 //
Probeset : 1641324_at
Accessions : protein= NP_476617;, nucleotide= NM_057269;
Pathway : 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix
Interpro : 0005102 // receptor binding // inferred from electronic annotation
FlyMine data for FBgn0002526.
BDGP gene expression has embryonic in situ data for LanA: 42 pix of staining in 26 body parts.
Homophila reports that CG10236 is a close match (1e-11) to human gene AUTS15;CASPR2;CDFE;CNTNAP2;NRXN4 (NP_054860), a gene associated with Cortical dysplasia-focal epilepsy syndrome, 610042 (3);{Autism, susceptibility to, 15}, 612100 (3).
BioGrid reports that CG10236 interacts with CG2540 CG4216 CG8793 CG2189 CG2189 .
TRiP has 1 RNAi stocks for FBgn0002526 available for purchase.
VDRC has 1 RNAi stocks for FBgn0002526 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain79 14 of 4 0.50Down
Head132 84 of 4 0.80None
Eye29 54 of 4 0.17Down
Thoracicoabdominal ganglion179 164 of 4 1.00None
Salivary gland18 22 of 4 0.11Down
Crop375 114 of 4 2.20Up
Midgut118 94 of 4 0.70Down
Tubule98 134 of 4 0.60Down
Hindgut187 34 of 4 1.10None
Heart656 314 of 4 3.80Up
Fat body108 164 of 4 0.63Down
Ovary199 94 of 4 1.20None
Testis61 54 of 4 0.40Down
Male accessory glands305 204 of 4 1.80Up
Virgin spermatheca37 14 of 4 0.22Down
Mated spermatheca59 44 of 4 0.35Down
Adult carcass172 84 of 4 1.00None
Larval CNS306 354 of 4 1.77Up
Larval Salivary gland106 34 of 4 0.62Down
Larval midgut156 94 of 4 0.91None
Larval tubule376 184 of 4 2.20Up
Larval hindgut1476 814 of 4 8.54Up
Larval fat body1076 734 of 4 6.20Up
Larval trachea434 294 of 4 2.51Up
Larval carcass491 154 of 4 2.84Up
S2 cells (growing)3284 854 of 419.00Up
Whole fly172 174 of 4

Looking for FBgn0002526. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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