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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0002719 through 18771 annotations produced 1 hits

Malic enzyme (Men):

Annotation Number : CG10120
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0002719
Gbrowse : chr3R:8538818-8548267 (-) // 100.0 //
Probeset : 1629095_a_at
Accessions : protein= NP_524880; /// NP_731739;, nucleotide= NM_080141; /// NM_169479;
Interpro : "0003824 // catalytic activity // inferred from electronic annotation /// 0004470 // malic enzyme activity // inferred f
FlyMine data for FBgn0002719.
BDGP gene expression has embryonic in situ data for Men: 29 pix of staining in 17 body parts.
Homophila reports that CG10120 is a close match (2e-160) to human gene ME2 (NP_002387), a gene associated with {Epilepsy, idopathic generalized, susceptibility to}, 600669 (3).
BioGrid reports that CG10120 interacts with CG13576 CG15177 CG6667 .
TRiP has 2 RNAi stocks for FBgn0002719 available for purchase.
VDRC has 1 RNAi stocks for FBgn0002719 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain456 164 of 4 0.50Down
Head1514 344 of 4 1.70Up
Eye868 1254 of 4 0.96None
Thoracicoabdominal ganglion557 94 of 4 0.60Down
Salivary gland51 42 of 4 0.06Down
Crop2003 654 of 4 2.20Up
Midgut545 294 of 4 0.60Down
Tubule1977 264 of 4 2.20Up
Hindgut945 264 of 4 1.00None
Heart2915 1534 of 4 3.23Up
Fat body3827 3564 of 4 4.24Up
Ovary479 114 of 4 0.50Down
Testis785 254 of 4 0.90Down
Male accessory glands276 214 of 4 0.30Down
Virgin spermatheca4206 1414 of 4 4.65Up
Mated spermatheca2897 2234 of 4 3.21Up
Adult carcass2830 774 of 4 3.10Up
Larval CNS672 614 of 4 0.74Down
Larval Salivary gland24 62 of 4 0.03Down
Larval midgut734 864 of 4 0.81None
Larval tubule1087 654 of 4 1.20None
Larval hindgut664 534 of 4 0.74Down
Larval fat body440 584 of 4 0.50Down
Larval trachea216 314 of 4 0.24Down
Larval carcass762 1254 of 4 0.84None
S2 cells (growing)950 154 of 4 1.05None
Whole fly903 174 of 4

Looking for FBgn0002719. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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