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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0003079 through 18771 annotations produced 1 hits

chrX:2234158-2237904 (+) // 100.0 // (Pole hole):

Annotation Number : CG2845
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : full length
Gbrowse : March 2006 (FlyBase/BDGP 5.3)
Probeset : 1627470_at
Accessions : protein= , nucleotide= NP_001036258; /// NP_001096867; /// NP_525047;
Pathway : "0002168 // instar larval development // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferr
Interpro : open tracheal system // traceable author statement /// 0007472 // wing disc morphogenesis // inferred from mutant pheno
FlyMine data for full length.
Homophila reports that CG2845 is a close match (5e-11) to human gene TEK;TIE2;VMCM (NP_000450), a gene associated with Venous malformations, multiple cutaneous and mucosal, 600195 (3).
BioGrid reports that CG2845 interacts with CG3166 CG3166 CG9554 CG9623 CG2275 CG3696 CG8118 CG5529 CG15793 CG15793 CG15793 CG15793 CG15793 CG10079 CG10079 CG10079 CG10079 CG10079 CG10079 CG9856 CG9856 CG9856 CG9856 CG2248 CG2248 CG13345 CG9375 CG9375 CG9375 CG9375 CG9375 CG9375 CG9375 CG9375 CG4385 CG4385 CG4385 CG4385 CG8553 CG7873 CG7873 CG7873 CG7873 CG7873 CG7873 CG5444 CG32211 CG5123 CG5123 CG3166 CG3166 CG4531 CG7508 CG6556 CG17051 CG4637 CG2899 CG2899 CG2899 CG8817 CG8817 CG7109 CG7109 CG7109 CG7109 CG10108 CG10108 CG17077 CG17077 CG17077 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG12559 CG4319 CG18497 CG18497 CG18497 CG1921 CG11502 CG11502 CG11502 CG11502 CG14026 CG1389 CG1389 CG4889 CG4889 CG31196 CG31196 CG31196 CG31196 CG6556 .

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain236 74 of 4 1.90Up
Head100 64 of 4 0.80None
Eye67 34 of 4 0.54Down
Thoracicoabdominal ganglion204 74 of 4 1.60Up
Salivary gland141 84 of 4 1.12None
Crop86 14 of 4 0.70Down
Midgut101 54 of 4 0.80None
Tubule111 34 of 4 0.90Down
Hindgut90 34 of 4 0.70Down
Heart55 24 of 4 0.44Down
Fat body69 94 of 4 0.55Down
Ovary235 64 of 4 1.90Up
Testis37 04 of 4 0.30Down
Male accessory glands81 44 of 4 0.60Down
Virgin spermatheca57 04 of 4 0.46Down
Mated spermatheca58 14 of 4 0.46Down
Adult carcass65 54 of 4 0.50Down
Larval CNS188 74 of 4 1.50Up
Larval Salivary gland112 24 of 4 0.89None
Larval midgut94 24 of 4 0.75Down
Larval tubule93 14 of 4 0.70Down
Larval hindgut93 14 of 4 0.74Down
Larval fat body63 34 of 4 0.50Down
Larval trachea84 34 of 4 0.68Down
Larval carcass83 24 of 4 0.66Down
S2 cells (growing)143 54 of 4 1.14None
Whole fly125 84 of 4

Looking for FBgn0003079. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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