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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0003091 through 18771 annotations produced 1 hits

protein kinase C (Pkc53E):

Annotation Number : CG6622
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0003091
Gbrowse : chr2R:12812458-12830668 (+) // 100.0 //
Probeset : 1632478_a_at
Accessions : protein= NP_001097350; /// NP_476682; /// NP_725626;, nucleotide= NM_001103880; /// NM_057334; /// NM_166201;
Interpro : 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred
FlyMine data for FBgn0003091.
Homophila reports that CG6622 is a close match (5e-11) to human gene CDS1;CHEK2;CHK2;LFS2;RAD53 (NP_665861), a gene associated with Li-Fraumeni syndrome, 609265 (3);Osteosarcoma, somatic, 259500 (3);Prostate cancer, familial, 176807 (3);{Breast and colorectal cancer, susceptibility to} (3);{Breast cancer, susceptibility to}, 114480 (3).
TRiP has 2 RNAi stocks for FBgn0003091 available for purchase.
VDRC has 2 RNAi stocks for FBgn0003091 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain335 184 of 4 7.30Up
Head123 164 of 4 2.70Up
Eye862 594 of 418.67Up
Thoracicoabdominal ganglion192 194 of 4 4.20Up
Salivary gland16 20 of 4 0.36Down
Crop8 21 of 4 0.20Down
Midgut14 13 of 4 0.30Down
Tubule7 00 of 4 0.20Down
Hindgut179 54 of 4 3.90Up
Heart73 64 of 4 1.58Up
Fat body14 53 of 4 0.31Down
Ovary23 04 of 4 0.50Down
Testis6 12 of 4 0.10Down
Male accessory glands933 434 of 420.20Up
Virgin spermatheca8 02 of 4 0.19Down
Mated spermatheca12 21 of 4 0.26Down
Adult carcass25 14 of 4 0.60Down
Larval CNS60 134 of 4 1.30None
Larval Salivary gland29 24 of 4 0.64Down
Larval midgut7 01 of 4 0.17Down
Larval tubule13 13 of 4 0.30Down
Larval hindgut46 44 of 4 1.00None
Larval fat body5 10 of 4 0.10Down
Larval trachea27 204 of 4 0.60None
Larval carcass23 24 of 4 0.51Down
S2 cells (growing)8 01 of 4 0.19Down
Whole fly46 24 of 4

Looking for FBgn0003091. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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