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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0003444 through 18771 annotations produced 1 hits



smoothened (smo):

Annotation Number : CG11561
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0003444
Gbrowse : chr2L:277587-282167 (+) // 100.0 //
Probeset : 1634442_at
Accessions : protein= NP_523443;, nucleotide= NM_078719;
Pathway : imaginal disc // traceable author statement /// 0048100 // wing disc anterior/posterior pattern formation // traceable
Interpro : 0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0
FlyMine data for FBgn0003444.
BDGP gene expression has embryonic in situ data for smo: 37 pix of staining in 12 body parts.
Homophila reports that CG11561 is a close match (9e-38) to human gene EVR1;FZD4 (NP_036325), a gene associated with Exudative vitreoretinopathy, 133780 (3);Retinopathy of prematurity, 133780 (3).
BioGrid reports that CG11561 interacts with CG17493 CG2986 CG6998 CG9885 CG9554 CG2411 CG2411 CG2411 CG2411 CG2411 CG2411 CG3412 CG4889 CG1708 CG6551 CG1708 .
TRiP has 1 RNAi stocks for FBgn0003444 available for purchase.
VDRC has 1 RNAi stocks for FBgn0003444 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain83 ± 14 of 4 0.70Down
Head75 ± 54 of 4 0.60Down
Eye90 ± 24 of 4 0.78Down
Thoracicoabdominal ganglion77 ± 34 of 4 0.70Down
Salivary gland66 ± 74 of 4 0.57Down
Crop161 ± 84 of 4 1.40Up
Midgut53 ± 44 of 4 0.50Down
Tubule81 ± 24 of 4 0.70Down
Hindgut106 ± 34 of 4 0.90None
Heart141 ± 24 of 4 1.21Up
Fat body170 ± 224 of 4 1.46Up
Ovary340 ± 64 of 4 2.90Up
Testis24 ± 14 of 4 0.20Down
Male accessory glands70 ± 24 of 4 0.60Down
Virgin spermatheca145 ± 164 of 4 1.25None
Mated spermatheca168 ± 134 of 4 1.44Up
Adult carcass96 ± 74 of 4 0.80None
Larval CNS216 ± 104 of 4 1.85Up
Larval Salivary gland72 ± 74 of 4 0.62Down
Larval midgut62 ± 14 of 4 0.54Down
Larval tubule126 ± 34 of 4 1.10None
Larval hindgut130 ± 24 of 4 1.12None
Larval fat body92 ± 64 of 4 0.80Down
Larval trachea403 ± 44 of 4 3.46Up
Larval carcass159 ± 74 of 4 1.36Up
S2 cells (growing)177 ± 24 of 4 1.52Up
Whole fly116 ± 54 of 4

Looking for FBgn0003444. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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