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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0003464 through 18771 annotations produced 1 hits

small optic lobe (sol):

Annotation Number : CG1391
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0003464
Gbrowse : chrX:21221356-21228933 (+) // 99.92 //
Probeset : 1634504_a_at
Accessions : protein= NP_001162813; /// NP_476737; /// NP_476738; /// NP_996524; /// NP_996525;, nucleotide= NM_001169342; /// NM_057389; /// NM_057390; /// NM_206801; /// NM_206802;
Pathway : 0005622 // intracellular // inferred from electronic annotation /// 0005622 // intracellular // inferred from sequence o
Interpro : 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0004198 // calcium-dependent
FlyMine data for FBgn0003464.
BDGP gene expression has embryonic in situ data for sol: 4 pix of staining in 1 body parts.
Homophila reports that CG1391 is a close match (4e-27) to human gene CAPN10 (NP_075573), a gene associated with {Diabetes mellitus, noninsulin-dependent}, 601283 (3).
BioGrid reports that CG1391 interacts with CG16728 CG16747 CG16947 CG4394 CG8942 CG14030 CG14641 CG14651 CG14996 CG15141 CG17075 CG17377 CG17666 CG17870 CG2116 CG2851 CG3630 CG3847 CG4216 CG4325 CG4755 Dmel CG34168 CG5080 CG5484 CG5569 CG5680 CG5701 CG6378 CG6570 CG6808 CG7109 CG7238 CG7518 CG7761 CG7856 CG7867 CG7928 CG7954 CG8368 CG8483 CG8598 CG9015 CG9036 CG9083 CG9398 CG9426 CG9572 CG9640 CG9653 CG9797 CG9941 .
TRiP has 1 RNAi stocks for FBgn0003464 available for purchase.
VDRC has 2 RNAi stocks for FBgn0003464 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain528 294 of 4 3.10Up
Head190 64 of 4 1.10None
Eye303 314 of 4 1.81Up
Thoracicoabdominal ganglion498 164 of 4 3.00Up
Salivary gland103 84 of 4 0.62Down
Crop173 84 of 4 1.00None
Midgut179 54 of 4 1.10None
Tubule209 184 of 4 1.30Up
Hindgut150 34 of 4 0.90None
Heart69 104 of 4 0.41Down
Fat body26 34 of 4 0.16Down
Ovary364 124 of 4 2.20Up
Testis50 24 of 4 0.30Down
Male accessory glands120 64 of 4 0.70Down
Virgin spermatheca70 54 of 4 0.42Down
Mated spermatheca85 154 of 4 0.51Down
Adult carcass92 54 of 4 0.60Down
Larval CNS344 244 of 4 2.05Up
Larval Salivary gland81 84 of 4 0.48Down
Larval midgut125 54 of 4 0.75Down
Larval tubule109 104 of 4 0.70Down
Larval hindgut125 94 of 4 0.75Down
Larval fat body147 74 of 4 0.90None
Larval trachea164 164 of 4 0.98None
Larval carcass113 54 of 4 0.67Down
S2 cells (growing)290 84 of 4 1.73Up
Whole fly167 94 of 4

Looking for FBgn0003464. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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