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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0003716 through 18771 annotations produced 1 hits

chr2L:5218999-5271353 (-) // 99.86 // (thickveins):

Annotation Number : CG14026
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : full length
Gbrowse : March 2006 (FlyBase/BDGP 5.3)
Probeset : 1636221_a_at
Accessions : protein= , nucleotide= NP_787989; /// NP_787990; /// NP_787991; /// NP_787992;
Pathway : "0001745 // compound eye morphogenesis // inferred from mutant phenotype /// 0001745 // compound eye morphogenesis // no
Interpro : imaginal disc // inferred from mutant phenotype /// 0007476 // imaginal disc-derived wing morphogenesis // inferred fro
FlyMine data for full length.
Homophila reports that CG14026 is a close match (8e-11) to human gene AUTS9;MET (NP_000236), a gene associated with Hepatocellular carcinoma, childhood type, 114550 (3);Renal cell carcinoma, papillary, familial and sporadic, 605074 (3);{Autism, suseptibility to, 9}, 611015 (3).
BioGrid reports that CG14026 interacts with CG11579 CG11579 CG11579 CG9885 CG9885 CG9885 CG9885 CG9885 CG9885 CG9885 CG9885 CG9885 CG9885 CG2275 CG14548 CG2845 CG7904 CG7904 CG7904 CG7904 CG1167 CG1891 CG1891 CG1891 CG1891 CG1891 CG1891 CG7734 CG7734 CG7734 CG7734 CG7734 CG7734 CG12530 CG5201 CG10079 CG10079 CG10574 CG12399 CG12399 CG12399 CG12399 CG1775 CG1775 CG1775 CG3936 CG3936 CG3936 CG3936 CG2699 CG2248 CG7413 CG5490 CG9653 CG9885 CG9885 CG5562 CG5562 CG5562 CG5562 CG5562 CG5562 CG4353 CG4353 CG16973 CG7393 CG1857 CG1857 CG7904 CG7904 CG7904 CG7904 CG1004 CG1004 CG31695 CG31695 CG7996 CG8428 CG1389 CG3830 CG7850 CG7850 .

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain344 154 of 4 1.30Up
Head268 104 of 4 1.00None
Eye319 114 of 4 1.20None
Thoracicoabdominal ganglion307 84 of 4 1.20None
Salivary gland191 154 of 4 0.72Down
Crop176 64 of 4 0.70Down
Midgut492 184 of 4 1.80Up
Tubule866 424 of 4 3.20Up
Hindgut447 54 of 4 1.70Up
Heart508 434 of 4 1.91Up
Fat body244 314 of 4 0.92None
Ovary437 24 of 4 1.60Up
Testis62 24 of 4 0.20Down
Male accessory glands258 34 of 4 1.00None
Virgin spermatheca537 214 of 4 2.02Up
Mated spermatheca615 614 of 4 2.31Up
Adult carcass261 84 of 4 1.00None
Larval CNS280 104 of 4 1.05None
Larval Salivary gland93 34 of 4 0.35Down
Larval midgut330 234 of 4 1.24None
Larval tubule638 184 of 4 2.40Up
Larval hindgut404 204 of 4 1.51Up
Larval fat body187 144 of 4 0.70Down
Larval trachea399 294 of 4 1.50Up
Larval carcass433 254 of 4 1.62Up
S2 cells (growing)155 14 of 4 0.58Down
Whole fly266 184 of 4

Looking for FBgn0003716. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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