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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0003896 through 18771 annotations produced 1 hits

islet (tup):

Annotation Number : CG10619
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0003896
Gbrowse : chr2L:18859514-18881256 (-) // 100.0 //
Probeset : 1625279_a_at
Accessions : protein= NP_476774; /// NP_476775;, nucleotide= NM_057426; /// NM_057427;
Pathway : DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II
Interpro : 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0
FlyMine data for FBgn0003896.
BDGP gene expression has embryonic in situ data for tup: 43 pix of staining in 27 body parts.
Homophila reports that CG10619 is a close match (1e-22) to human gene LHX3 (NP_835258), a gene associated with Pituitary hormone deficiency, combined, with rigid cervical spine, 262600 (3).
BioGrid reports that CG10619 interacts with CG10699 CG11883 CG14816 CG3924 CG6203 CG32369 CG4303 CG5009 CG5333 CG7787 CG8376 CG1389 CG2762 .
VDRC has 2 RNAi stocks for FBgn0003896 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain87 74 of 418.80Up
Head15 04 of 4 3.30Up
Eye0 00 of 4 0.21Down
Thoracicoabdominal ganglion20 14 of 4 4.30Up
Salivary gland6 10 of 4 1.31None
Crop63 74 of 413.60Up
Midgut8 12 of 4 1.70None
Tubule1 00 of 4 0.30Down
Hindgut6 04 of 4 1.50None
Heart57 44 of 412.38Up
Fat body5 21 of 4 1.13None
Ovary0 00 of 4 0.10Down
Testis2 00 of 4 0.60None
Male accessory glands1 00 of 4 0.30Down
Virgin spermatheca0 00 of 4 0.19Down
Mated spermatheca0 00 of 4 0.06Down
Adult carcass7 30 of 4 1.50None
Larval CNS86 254 of 418.40Up
Larval Salivary gland2 00 of 4 0.43Down
Larval midgut9 12 of 4 1.98Up
Larval tubule1 00 of 4 0.30Down
Larval hindgut75 54 of 416.18Up
Larval fat body1 00 of 4 0.30Down
Larval trachea5 13 of 4 1.16None
Larval carcass12 14 of 4 2.71Up
S2 cells (growing)0 00 of 4 0.05Down
Whole fly4 02 of 4

Looking for FBgn0003896. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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