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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0004102 through 18771 annotations produced 1 hits

orthodenticle (oc):

Annotation Number : CG12154
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004102
Gbrowse : chrX:8525372-8544683 (-) // 100.0 //
Probeset : 1626946_at
Accessions : protein= NP_001014727;, nucleotide= NM_001014727;
Pathway : DNA-dependent // inferred from sequence or structural similarity /// 0006355 // regulation of transcription
Interpro : DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred fr
FlyMine data for FBgn0004102.
Homophila reports that CG12154 is a close match (3e-11) to human gene KTCN;PPCD;PPD;RINX;VSX1 (NP_055403), a gene associated with Corneal dystrophy, hereditary polymorphous posterior, 122000 (3);Craniofacial anomalies, empty sella turcica, corneal endothelial changes, and abnormal retinal and auditory bipolar cells (3);Keratoconus, 148300 (3).
BioGrid reports that CG12154 interacts with CG13929 CG2984 CG31247 CG9875 CG16724 .
TRiP has 2 RNAi stocks for FBgn0004102 available for purchase.
VDRC has 3 RNAi stocks for FBgn0004102 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain80 24 of 4 9.00Up
Head43 24 of 4 4.90Up
Eye174 234 of 419.47Up
Thoracicoabdominal ganglion24 14 of 4 2.70Up
Salivary gland21 31 of 4 2.37Up
Crop4 10 of 4 0.50None
Midgut1 00 of 4 0.20Down
Tubule4 10 of 4 0.50Down
Hindgut3 10 of 4 0.40None
Heart4 10 of 4 0.51None
Fat body11 50 of 4 1.23None
Ovary2 10 of 4 0.30Down
Testis8 03 of 4 0.90None
Male accessory glands6 20 of 4 0.80None
Virgin spermatheca12 03 of 4 1.38None
Mated spermatheca11 31 of 4 1.28None
Adult carcass1 00 of 4 0.10Down
Larval CNS92 44 of 410.32Up
Larval Salivary gland12 22 of 4 1.37None
Larval midgut1 00 of 4 0.15Down
Larval tubule4 10 of 4 0.50None
Larval hindgut6 10 of 4 0.68None
Larval fat body5 20 of 4 0.70None
Larval trachea7 31 of 4 0.85None
Larval carcass18 14 of 4 2.11Up
S2 cells (growing)2 00 of 4 0.27Down
Whole fly9 12 of 4

Looking for FBgn0004102. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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