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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0004168 through 18771 annotations produced 1 hits

serotonin-receptor-2A (5-HT1A):

Annotation Number : CG16720
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004168
Gbrowse : chr2R:14954663-15009463 (+) // 100.0 //
Probeset : 1638131_s_at
Accessions : protein= NP_476802; /// NP_725849;, nucleotide= NM_057454; /// NM_166322;
Pathway : sleep // inferred from mutant phenotype"
Interpro : 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // non-trac
FlyMine data for FBgn0004168.
BDGP gene expression has embryonic in situ data for 5-HT1A: 4 pix of staining in 1 body parts.
Homophila reports that CG16720 is a close match (9e-12) to human gene ADRB3 (NP_000016), a gene associated with {Obesity, susceptibility to}, 601665 (3).
TRiP has 2 RNAi stocks for FBgn0004168 available for purchase.
VDRC has 1 RNAi stocks for FBgn0004168 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain377 234 of 436.40Up
Head72 64 of 4 7.00Up
Eye13 14 of 4 1.29None
Thoracicoabdominal ganglion245 144 of 423.60Up
Salivary gland18 52 of 4 1.75None
Crop8 13 of 4 0.80None
Midgut1 00 of 4 0.10Down
Tubule9 13 of 4 0.90None
Hindgut5 03 of 4 0.50Down
Heart3 00 of 4 0.30Down
Fat body26 94 of 4 2.58Up
Ovary1 00 of 4 0.10Down
Testis2 00 of 4 0.20Down
Male accessory glands13 13 of 4 1.30None
Virgin spermatheca10 04 of 4 1.04None
Mated spermatheca14 34 of 4 1.35None
Adult carcass7 32 of 4 0.80None
Larval CNS229 154 of 422.11Up
Larval Salivary gland7 03 of 4 0.70Down
Larval midgut2 01 of 4 0.21Down
Larval tubule3 10 of 4 0.30Down
Larval hindgut14 34 of 4 1.42None
Larval fat body3 10 of 4 0.40Down
Larval trachea2 10 of 4 0.22Down
Larval carcass2 00 of 4 0.24Down
S2 cells (growing)2 01 of 4 0.28Down
Whole fly10 04 of 4

Looking for FBgn0004168. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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