FlyAtlas: the Drosophila gene expression atlas

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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

Searching for FBGN0004369 through 18771 annotations produced 5 hits

Protein tyrosine phosphatase 99A (Ptp99A):

Annotation Number : CG2005
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004369
Gbrowse : chr3R:25283290-25312853 (+) // 100.0 //
Probeset : 1637204_at
Accessions : protein= NP_001014683; /// NP_476816; /// NP_651691; /// NP_733288; /// NP_996302;, nucleotide= NM_001014683; /// NM_001014683; /// NM_057468; /// NM_057468; /// NM_143434; /// NM_170409; /// NM_170409; /// NM_206579; /// NM_206579;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or str
Interpro : 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine ph
FlyMine data for FBgn0004369.
Homophila reports that CG2005 is a close match (2e-42) to human gene LYP;PEP;PTPN22;PTPN8 (NP_036543), a gene associated with {Diabetes mellitus, insulin-dependent, susceptibility to}, 222100 (3);{Rheumatoid arthritis, susceptibility to}, 180300 (3);{Systemic lupus erythematosus, susceptibility to}, 152700 (3).
TRiP has 2 RNAi stocks for FBgn0004369 available for purchase.
VDRC has 7 RNAi stocks for FBgn0004369 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	806 ± 49	4 of 4	23.30	Up
Head	165 ± 9	4 of 4	4.80	Up
Eye	252 ± 7	4 of 4	7.31	Up
Thoracicoabdominal ganglion	549 ± 20	4 of 4	15.90	Up
Salivary gland	72 ± 2	4 of 4	2.10	Up
Crop	94 ± 5	4 of 4	2.70	Up
Midgut	23 ± 1	4 of 4	0.70	None
Tubule	23 ± 1	4 of 4	0.70	Down
Hindgut	70 ± 4	4 of 4	2.10	Up
Heart	66 ± 6	4 of 4	1.93	Up
Fat body	28 ± 4	4 of 4	0.83	None
Ovary	5 ± 0	2 of 4	0.20	Down
Testis	6 ± 0	0 of 4	0.20	Down
Male accessory glands	126 ± 12	4 of 4	3.70	Up
Virgin spermatheca	80 ± 7	4 of 4	2.33	Up
Mated spermatheca	77 ± 6	4 of 4	2.25	Up
Adult carcass	50 ± 5	4 of 4	1.50	None
Larval CNS	450 ± 55	4 of 4	13.05	Up
Larval Salivary gland	24 ± 3	4 of 4	0.71	None
Larval midgut	18 ± 1	4 of 4	0.53	None
Larval tubule	29 ± 2	4 of 4	0.90	None
Larval hindgut	35 ± 1	4 of 4	1.02	None
Larval fat body	31 ± 2	4 of 4	0.90	None
Larval trachea	68 ± 15	4 of 4	1.99	Up
Larval carcass	32 ± 6	4 of 4	0.95	None
S2 cells (growing)	29 ± 1	4 of 4	0.86	None
Whole fly	34 ± 5	4 of 4

Protein tyrosine phosphatase 99A (Ptp99A):

Annotation Number : CG11517
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004369
Gbrowse : chr3R:25256446-25256973 (+) // 100.0 //
Probeset : 1624710_at
Accessions : protein= NP_001014683; /// NP_476816; /// NP_651691; /// NP_733288; /// NP_996302;, nucleotide= NM_001014683; /// NM_001014683; /// NM_057468; /// NM_057468; /// NM_143434; /// NM_170409; /// NM_170409; /// NM_206579; /// NM_206579;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or str
Interpro : 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine ph
FlyMine data for FBgn0004369.
Homophila reports that CG11517 is a close match (1e-13) to human gene ROBO3;RBIG1;RIG1;HGPPS (NP_071765), a gene associated with Gaze palsy, horizontal, with progressive scoliosis, 607313 (3).
TRiP has 2 RNAi stocks for FBgn0004369 available for purchase.
VDRC has 7 RNAi stocks for FBgn0004369 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	8 ± 1	2 of 4	2.00	None
Head	6 ± 1	0 of 4	1.40	None
Eye	7 ± 1	1 of 4	1.72	None
Thoracicoabdominal ganglion	9 ± 1	0 of 4	2.10	Up
Salivary gland	13 ± 4	0 of 4	2.90	None
Crop	4 ± 1	0 of 4	0.90	None
Midgut	7 ± 0	0 of 4	1.60	None
Tubule	6 ± 0	0 of 4	1.30	Up
Hindgut	5 ± 1	0 of 4	1.20	None
Heart	4 ± 1	0 of 4	0.96	None
Fat body	10 ± 2	0 of 4	2.25	Up
Ovary	3 ± 1	0 of 4	0.80	None
Testis	2 ± 0	0 of 4	0.50	None
Male accessory glands	10 ± 1	0 of 4	2.30	Up
Virgin spermatheca	8 ± 1	1 of 4	1.82	None
Mated spermatheca	6 ± 1	0 of 4	1.46	None
Adult carcass	10 ± 2	0 of 4	2.30	None
Larval CNS	4 ± 1	1 of 4	1.07	None
Larval Salivary gland	8 ± 1	0 of 4	1.84	None
Larval midgut	6 ± 2	1 of 4	1.31	None
Larval tubule	6 ± 0	0 of 4	1.40	None
Larval hindgut	6 ± 1	0 of 4	1.41	None
Larval fat body	7 ± 3	0 of 4	1.60	None
Larval trachea	3 ± 1	0 of 4	0.76	None
Larval carcass	9 ± 1	0 of 4	2.08	Up
S2 cells (growing)	0 ± 0	0 of 4	0.18	None
Whole fly	4 ± 1	0 of 4

Protein tyrosine phosphatase 99A (Ptp99A):

Annotation Number : CG2005
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004369
Gbrowse : chr3R:25287534-25310461 (+) // 100.0 //
Probeset : 1632003_a_at
Accessions : protein= NP_001014683; /// NP_476816; /// NP_651691; /// NP_733288; /// NP_996302;, nucleotide= NM_001014683; /// NM_001014683; /// NM_057468; /// NM_057468; /// NM_143434; /// NM_170409; /// NM_170409; /// NM_206579; /// NM_206579;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or str
Interpro : 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine ph
FlyMine data for FBgn0004369.
Homophila reports that CG2005 is a close match (2e-42) to human gene LYP;PEP;PTPN22;PTPN8 (NP_036543), a gene associated with {Diabetes mellitus, insulin-dependent, susceptibility to}, 222100 (3);{Rheumatoid arthritis, susceptibility to}, 180300 (3);{Systemic lupus erythematosus, susceptibility to}, 152700 (3).
TRiP has 2 RNAi stocks for FBgn0004369 available for purchase.
VDRC has 7 RNAi stocks for FBgn0004369 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	49 ± 1	4 of 4	0.70	Down
Head	40 ± 5	4 of 4	0.60	Down
Eye	16 ± 1	4 of 4	0.25	Down
Thoracicoabdominal ganglion	47 ± 4	4 of 4	0.70	Down
Salivary gland	58 ± 4	4 of 4	0.89	None
Crop	76 ± 4	4 of 4	1.20	None
Midgut	39 ± 1	4 of 4	0.60	Down
Tubule	58 ± 2	4 of 4	0.90	Down
Hindgut	60 ± 1	4 of 4	0.90	None
Heart	35 ± 2	4 of 4	0.54	Down
Fat body	55 ± 8	4 of 4	0.84	None
Ovary	102 ± 3	4 of 4	1.60	Up
Testis	12 ± 0	4 of 4	0.20	Down
Male accessory glands	108 ± 3	4 of 4	1.60	Up
Virgin spermatheca	36 ± 2	4 of 4	0.56	Down
Mated spermatheca	38 ± 2	4 of 4	0.58	Down
Adult carcass	67 ± 5	4 of 4	1.00	None
Larval CNS	55 ± 3	4 of 4	0.84	None
Larval Salivary gland	42 ± 2	4 of 4	0.65	Down
Larval midgut	27 ± 1	4 of 4	0.41	Down
Larval tubule	39 ± 2	4 of 4	0.60	Down
Larval hindgut	41 ± 0	4 of 4	0.63	Down
Larval fat body	36 ± 2	4 of 4	0.60	Down
Larval trachea	19 ± 2	4 of 4	0.30	Down
Larval carcass	36 ± 6	4 of 4	0.56	Down
S2 cells (growing)	122 ± 3	4 of 4	1.87	Up
Whole fly	65 ± 3	4 of 4

Protein tyrosine phosphatase 99A (Ptp99A):

Annotation Number : CT35612
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004369
Gbrowse : chr3R:25242176-25242855 (+) // 100.0 //
Probeset : 1630017_at
Accessions : protein= NP_001014683; /// NP_476816; /// NP_651691; /// NP_733288; /// NP_996302;, nucleotide= NM_001014683; /// NM_001014683; /// NM_057468; /// NM_057468; /// NM_143434; /// NM_170409; /// NM_170409; /// NM_206579; /// NM_206579;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or str
Interpro : 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine ph
FlyMine data for FBgn0004369.
TRiP has 2 RNAi stocks for FBgn0004369 available for purchase.
VDRC has 7 RNAi stocks for FBgn0004369 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	8 ± 1	2 of 4	4.00	Up
Head	4 ± 1	0 of 4	1.90	None
Eye	3 ± 1	0 of 4	1.39	None
Thoracicoabdominal ganglion	6 ± 0	0 of 4	2.90	Up
Salivary gland	13 ± 2	1 of 4	6.02	Up
Crop	10 ± 0	1 of 4	4.60	Up
Midgut	4 ± 1	0 of 4	1.80	None
Tubule	4 ± 1	0 of 4	1.90	None
Hindgut	3 ± 1	0 of 4	1.70	None
Heart	5 ± 2	0 of 4	2.35	None
Fat body	1 ± 0	0 of 4	0.61	None
Ovary	2 ± 1	0 of 4	1.10	None
Testis	3 ± 1	0 of 4	1.70	None
Male accessory glands	8 ± 2	1 of 4	3.90	None
Virgin spermatheca	2 ± 1	0 of 4	1.27	None
Mated spermatheca	2 ± 1	0 of 4	1.23	None
Adult carcass	8 ± 4	0 of 4	3.80	None
Larval CNS	4 ± 1	0 of 4	1.95	Up
Larval Salivary gland	3 ± 1	0 of 4	1.47	None
Larval midgut	5 ± 2	0 of 4	2.39	None
Larval tubule	4 ± 1	0 of 4	2.10	None
Larval hindgut	2 ± 1	0 of 4	1.25	None
Larval fat body	4 ± 1	0 of 4	2.20	None
Larval trachea	2 ± 2	0 of 4	1.24	None
Larval carcass	6 ± 1	0 of 4	2.89	None
S2 cells (growing)	3 ± 1	1 of 4	1.57	None
Whole fly	2 ± 0	0 of 4

Protein tyrosine phosphatase 99A (Ptp99A):

Annotation Number : CG11516
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004369
Gbrowse : chr3R:25252423-25254477 (+) // 100.0 //
Probeset : 1628770_at
Accessions : protein= NP_001014683; /// NP_476816; /// NP_651691; /// NP_733288; /// NP_996302;, nucleotide= NM_001014683; /// NM_001014683; /// NM_057468; /// NM_057468; /// NM_143434; /// NM_170409; /// NM_170409; /// NM_206579; /// NM_206579;
Pathway : 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or str
Interpro : 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine ph
FlyMine data for FBgn0004369.
BioGrid reports that CG11516 interacts with CG10975 CG10975 .
TRiP has 2 RNAi stocks for FBgn0004369 available for purchase.
VDRC has 7 RNAi stocks for FBgn0004369 available for purchase.

Tissue	mRNA Signal	Present Call	Enrichment	Affy Call
Brain	11 ± 1	4 of 4	2.20	None
Head	5 ± 1	1 of 4	1.10	None
Eye	9 ± 1	2 of 4	1.71	None
Thoracicoabdominal ganglion	7 ± 0	3 of 4	1.40	None
Salivary gland	2 ± 0	0 of 4	0.53	None
Crop	7 ± 2	0 of 4	1.40	None
Midgut	12 ± 1	3 of 4	2.40	Up
Tubule	6 ± 1	1 of 4	1.20	None
Hindgut	7 ± 1	1 of 4	1.30	None
Heart	6 ± 0	0 of 4	1.25	None
Fat body	7 ± 2	1 of 4	1.41	None
Ovary	3 ± 0	0 of 4	0.70	None
Testis	5 ± 1	0 of 4	0.90	None
Male accessory glands	5 ± 1	0 of 4	1.00	None
Virgin spermatheca	3 ± 0	0 of 4	0.66	None
Mated spermatheca	5 ± 0	0 of 4	1.07	None
Adult carcass	6 ± 1	0 of 4	1.10	None
Larval CNS	4 ± 2	2 of 4	0.79	None
Larval Salivary gland	8 ± 1	2 of 4	1.61	None
Larval midgut	12 ± 3	4 of 4	2.40	None
Larval tubule	4 ± 1	0 of 4	0.80	None
Larval hindgut	6 ± 1	2 of 4	1.21	None
Larval fat body	4 ± 1	1 of 4	0.80	None
Larval trachea	2 ± 3	0 of 4	0.56	None
Larval carcass	5 ± 1	0 of 4	0.97	None
S2 cells (growing)	4 ± 0	0 of 4	0.78	None
Whole fly	5 ± 2	2 of 4

Looking for FBgn0004369. 5 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720