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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0004430 through 18771 annotations produced 1 hits

Lysozyme S (LysS):

Annotation Number : CG1165
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004430
Gbrowse : chr3L:1227746-1228246 (+) // 100.0 //
Probeset : 1634493_at
Accessions : protein= NP_476829;, nucleotide= NM_057481;
Interpro : "0003796 // lysozyme activity // inferred from electronic annotation /// 0003796 // lysozyme activity // inferred from s
FlyMine data for FBgn0004430.
BDGP gene expression has embryonic in situ data for LysS: 8 pix of staining in 1 body parts.
Homophila reports that CG1165 is a close match (3e-17) to human gene LYZ (NP_000230), a gene associated with Amyloidosis, renal, 105200 (3).
VDRC has 2 RNAi stocks for FBgn0004430 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain1 00 of 4 0.10Down
Head1 00 of 4 0.10Down
Eye2 20 of 4 0.14Down
Thoracicoabdominal ganglion1 00 of 4 0.10Down
Salivary gland50 70 of 4 2.44Up
Crop6 20 of 4 0.30Down
Midgut80 54 of 4 3.90Up
Tubule3 10 of 4 0.10Down
Hindgut3 00 of 4 0.20Down
Heart1 00 of 4 0.06Down
Fat body6 60 of 4 0.33Down
Ovary1 00 of 4 0.10Down
Testis7 00 of 4 0.30Down
Male accessory glands22 50 of 4 1.10None
Virgin spermatheca1 00 of 4 0.06Down
Mated spermatheca2 00 of 4 0.10Down
Adult carcass13 30 of 4 0.70None
Larval CNS6 30 of 4 0.32Down
Larval Salivary gland13 10 of 4 0.66None
Larval midgut5221 2624 of 4252.55Up
Larval tubule15 40 of 4 0.70None
Larval hindgut25 42 of 4 1.22None
Larval fat body59 521 of 4 2.90None
Larval trachea88 1502 of 4 4.28None
Larval carcass17 20 of 4 0.87None
S2 cells (growing)2 00 of 4 0.10Down
Whole fly20 42 of 4

Looking for FBgn0004430. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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