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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0004516 through 18771 annotations produced 1 hits

Glutamic acid decarboxylase 1 (Gad1):

Annotation Number : CG14994
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004516
Gbrowse : chr3L:4074072-4088744 (-) // 99.88 //
Probeset : 1627818_s_at
Accessions : protein= NP_523914; /// NP_728930; /// NP_728931;, nucleotide= NM_079190; /// NM_168055; /// NM_168056;
Interpro : 0003824 // catalytic activity // inferred from electronic annotation /// 0004351 // glutamate decarboxylase activity //
FlyMine data for FBgn0004516.
BDGP gene expression has embryonic in situ data for Gad1: 14 pix of staining in 5 body parts.
Homophila reports that CG14994 is a close match (2e-30) to human gene GAD1;SCP (NP_038473), a gene associated with Cerebral palsy, spastic, symmetric, autosomal recessive, 603513 (3).
BioGrid reports that CG14994 interacts with CG7191 CG9986 .
TRiP has 1 RNAi stocks for FBgn0004516 available for purchase.
VDRC has 1 RNAi stocks for FBgn0004516 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain2478 714 of 412.90Up
Head1119 844 of 4 5.80Up
Eye84 174 of 4 0.44Down
Thoracicoabdominal ganglion3766 1034 of 419.60Up
Salivary gland12 12 of 4 0.06Down
Crop6 12 of 4 0.00Down
Midgut3 10 of 4 0.00Down
Tubule2 00 of 4 0.00Down
Hindgut1 10 of 4 0.00Down
Heart1 00 of 4 0.01Down
Fat body10 33 of 4 0.06Down
Ovary1 00 of 4 0.00Down
Testis1 00 of 4 0.00Down
Male accessory glands2 10 of 4 0.00Down
Virgin spermatheca6 11 of 4 0.03Down
Mated spermatheca2 00 of 4 0.01Down
Adult carcass64 154 of 4 0.30Down
Larval CNS1296 604 of 4 6.73Up
Larval Salivary gland5 12 of 4 0.03Down
Larval midgut7 10 of 4 0.04Down
Larval tubule3 00 of 4 0.00Down
Larval hindgut1 00 of 4 0.01Down
Larval fat body6 20 of 4 0.00Down
Larval trachea2 10 of 4 0.01Down
Larval carcass4 21 of 4 0.02Down
S2 cells (growing)2 00 of 4 0.01Down
Whole fly192 124 of 4

Looking for FBgn0004516. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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