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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0004567 through 18771 annotations produced 1 hits

sloppy-paired (slp2):

Annotation Number : CG2939
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004567
Gbrowse : chr2L:3836841-3839201 (+) // 100.0 //
Probeset : 1627053_at
Accessions : protein= NP_476834;, nucleotide= NM_057486;
Pathway : DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred fr
Interpro : 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // non-traceable author sta
FlyMine data for FBgn0004567.
BDGP gene expression has embryonic in situ data for slp2: 32 pix of staining in 20 body parts.
Homophila reports that CG2939 is a close match (6e-11) to human gene AIID;FOXP3;IPEX;PIDX;XPID (NP_054728), a gene associated with Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked, 304790 (3);{Diabetes mellitus, type I, susceptibility to}, 222100 (3).
BioGrid reports that CG2939 interacts with CG4889 CG4889 .
TRiP has 1 RNAi stocks for FBgn0004567 available for purchase.
VDRC has 2 RNAi stocks for FBgn0004567 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain31 14 of 4 8.80Up
Head28 04 of 4 8.00Up
Eye46 44 of 413.05Up
Thoracicoabdominal ganglion27 14 of 4 7.90Up
Salivary gland15 10 of 4 4.37Up
Crop8 11 of 4 2.40Up
Midgut1 10 of 4 0.50None
Tubule3 00 of 4 1.10None
Hindgut4 01 of 4 1.30None
Heart1 10 of 4 0.48None
Fat body14 54 of 4 3.99Up
Ovary0 00 of 4 0.00Down
Testis0 00 of 4 0.20None
Male accessory glands2 20 of 4 0.80None
Virgin spermatheca6 11 of 4 1.81None
Mated spermatheca5 01 of 4 1.60None
Adult carcass7 21 of 4 2.10None
Larval CNS229 394 of 465.02Up
Larval Salivary gland3 11 of 4 1.08None
Larval midgut4 02 of 4 1.23None
Larval tubule2 01 of 4 0.70None
Larval hindgut3 11 of 4 0.87None
Larval fat body4 10 of 4 1.30None
Larval trachea1 10 of 4 0.48None
Larval carcass11 14 of 4 3.35Up
S2 cells (growing)1 00 of 4 0.35None
Whole fly3 01 of 4

Looking for FBgn0004567. 1 entries matched from 18771, in 1 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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