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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0004598 through 18771 annotations produced 1 hits



Furin-like protease (Fur2):

Annotation Number : CG18734
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0004598
Gbrowse : chrX:16267120-16275564 (+) // 100.0 //
Probeset : 1640470_s_at
Accessions : protein= NP_001162773; /// NP_001162774; /// NP_523368; /// NP_727963; /// NP_727964; /// NP_727965; /// NP_727966; /// NP_727967; /// NP_996486;, nucleotide= NM_001169302; /// NM_001169303; /// NM_078644; /// NM_167506; /// NM_167507; /// NM_167508; /// NM_167509; /// NM_167510; /// NM_206763;
Pathway : 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from e
Interpro : 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0004252 // serine-type endopeptidase act
FlyMine data for FBgn0004598.
Homophila reports that CG18734 is a close match (7e-11) to human gene HHF5;INSR (NP_001073285), a gene associated with Diabetes mellitus, insulin-resistant, with acanthosis nigricans, 610549 (3);Hyperinsulinemic hypoglycemia, familial, 5, 609968 (3);Leprechaunism, 246200 (3);Rabson-Mendenhall syndrome, 262190 (3).
BioGrid reports that CG18734 interacts with CG3056 CG32705 CG3780 CG3858 CG4820 CG6569 CG7605 .
TRiP has 2 RNAi stocks for FBgn0004598 available for purchase.
VDRC has 2 RNAi stocks for FBgn0004598 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain413 ± 104 of 4 1.40Up
Head292 ± 94 of 4 1.00None
Eye272 ± 184 of 4 0.94None
Thoracicoabdominal ganglion388 ± 74 of 4 1.30Up
Salivary gland42 ± 54 of 4 0.15Down
Crop136 ± 64 of 4 0.50Down
Midgut25 ± 24 of 4 0.10Down
Tubule15 ± 33 of 4 0.10Down
Hindgut180 ± 44 of 4 0.60Down
Heart168 ± 44 of 4 0.58Down
Fat body319 ± 234 of 4 1.10None
Ovary667 ± 64 of 4 2.30Up
Testis22 ± 34 of 4 0.10Down
Male accessory glands27 ± 24 of 4 0.10Down
Virgin spermatheca252 ± 124 of 4 0.87None
Mated spermatheca237 ± 64 of 4 0.82None
Adult carcass171 ± 174 of 4 0.60Down
Larval CNS273 ± 234 of 4 0.94None
Larval Salivary gland59 ± 64 of 4 0.20Down
Larval midgut29 ± 04 of 4 0.10Down
Larval tubule14 ± 14 of 4 0.00Down
Larval hindgut256 ± 54 of 4 0.88None
Larval fat body73 ± 64 of 4 0.30Down
Larval trachea397 ± 304 of 4 1.37Up
Larval carcass174 ± 104 of 4 0.60Down
S2 cells (growing)366 ± 84 of 4 1.26Up
Whole fly290 ± 224 of 4

Looking for FBgn0004598. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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