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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0005558 through 18771 annotations produced 1 hits

eyeless (ey):

Annotation Number : CG1464
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0005558
Gbrowse : chr4:718314-741783 (+) // 99.86 //
Probeset : 1628973_a_at
Accessions : protein= NP_001014693; /// NP_001014694; /// NP_524628; /// NP_726607;, nucleotide= NM_001014693; /// NM_001014694; /// NM_079889; /// NM_166789;
Pathway : DNA-dependent // inferred from sequence or structural similarity /// 0006355 // regulation of transcription
Interpro : DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred fr
FlyMine data for FBgn0005558.
Homophila reports that CG1464 is a close match (1e-11) to human gene KTCN;PPCD;PPD;RINX;VSX1 (NP_055403), a gene associated with Corneal dystrophy, hereditary polymorphous posterior, 122000 (3);Craniofacial anomalies, empty sella turcica, corneal endothelial changes, and abnormal retinal and auditory bipolar cells (3);Keratoconus, 148300 (3).
BioGrid reports that CG1464 interacts with CG5222 CG17612 CG2998 CG32016 CG32425 CG33146 CG4254 CG6141 CG6202 CG6770 CG8409 CG17450 CG32819 CG32820 CG1028 CG9554 CG9554 CG9554 CG9554 CG9554 CG9554 CG9554 CG9554 CG9885 CG9885 CG9885 CG9885 CG10488 CG10488 CG10488 CG10488 CG3388 CG11121 CG4637 CG4637 CG2125 CG18455 CG9653 CG4952 CG4952 CG6963 CG31481 CG31481 CG31481 CG31481 CG11186 CG11186 CG11186 CG9047 .
TRiP has 2 RNAi stocks for FBgn0005558 available for purchase.
VDRC has 2 RNAi stocks for FBgn0005558 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain177 54 of 422.00Up
Head49 23 of 4 6.20Up
Eye86 24 of 410.80Up
Thoracicoabdominal ganglion59 34 of 4 7.40Up
Salivary gland4 10 of 4 0.60None
Crop1 00 of 4 0.20None
Midgut4 00 of 4 0.50None
Tubule2 00 of 4 0.20Down
Hindgut3 00 of 4 0.40None
Heart0 00 of 4 0.10None
Fat body2 00 of 4 0.30None
Ovary2 00 of 4 0.30None
Testis3 20 of 4 0.40None
Male accessory glands2 00 of 4 0.30None
Virgin spermatheca0 00 of 4 0.10None
Mated spermatheca1 00 of 4 0.18None
Adult carcass2 00 of 4 0.30None
Larval CNS136 44 of 416.98Up
Larval Salivary gland2 00 of 4 0.31None
Larval midgut2 00 of 4 0.29None
Larval tubule1 00 of 4 0.20None
Larval hindgut1 00 of 4 0.22None
Larval fat body7 10 of 4 0.90None
Larval trachea2 20 of 4 0.32None
Larval carcass1 00 of 4 0.18None
S2 cells (growing)1 00 of 4 0.21None
Whole fly8 20 of 4

Looking for FBgn0005558. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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