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FlyAtlas: the Drosophila gene expression atlas

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Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.


This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)


Searching for FBGN0010222 through 18771 annotations produced 1 hits



NAD-dependent methylenetetrahydrofolate dehydrogenase (Nmdmc):

Annotation Number : CG18466
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010222
Gbrowse : chr3R:4868231-4876271 (-) // 100.0 //
Probeset : 1640775_a_at
Accessions : protein= NP_476929; /// NP_476930;, nucleotide= NM_057581; /// NM_057582;
Pathway : 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // non-traceabl
Interpro : 0000287 // magnesium ion binding // non-traceable author statement /// 0000287 // magnesium ion binding // inferred from
FlyMine data for FBgn0010222.
BDGP gene expression has embryonic in situ data for Nmdmc: 18 pix of staining in 5 body parts.
Homophila reports that CG18466 is a close match (2e-50) to human gene MTHFC;MTHFD (NP_005947), a gene associated with {Abruptio placentae, susceptibility to} (3);{Spina bifida, folate-sensitive, susceptibility to}, 601634 (3).
VDRC has 3 RNAi stocks for FBgn0010222 available for purchase.


TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain79 ± 44 of 4 0.70Down
Head160 ± 334 of 4 1.40None
Eye197 ± 224 of 4 1.72Up
Thoracicoabdominal ganglion96 ± 44 of 4 0.80Down
Salivary gland78 ± 134 of 4 0.68None
Crop172 ± 74 of 4 1.50Up
Midgut31 ± 24 of 4 0.30Down
Tubule51 ± 43 of 4 0.40Down
Hindgut223 ± 164 of 4 1.90Up
Heart219 ± 154 of 4 1.91Up
Fat body317 ± 1194 of 4 2.77Up
Ovary134 ± 24 of 4 1.20Up
Testis86 ± 64 of 4 0.80Down
Male accessory glands137 ± 124 of 4 1.20None
Virgin spermatheca635 ± 1824 of 4 5.54None
Mated spermatheca287 ± 1554 of 4 2.50None
Adult carcass116 ± 144 of 4 1.00None
Larval CNS187 ± 84 of 4 1.63Up
Larval Salivary gland117 ± 104 of 4 1.02None
Larval midgut143 ± 154 of 4 1.25None
Larval tubule63 ± 64 of 4 0.60Down
Larval hindgut415 ± 764 of 4 3.62Up
Larval fat body1069 ± 1214 of 4 9.30Up
Larval trachea210 ± 434 of 4 1.83Up
Larval carcass614 ± 1654 of 4 5.35None
S2 cells (growing)186 ± 44 of 4 1.62Up
Whole fly114 ± 54 of 4

Looking for FBgn0010222. 1 entries matched from 18771, in 1 s.


Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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