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FlyAtlas: the Drosophila gene expression atlas

University of Glasgow
Biotechnology & Biological Sciences Research Council
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Latest news: FlyAtlas2 : A Database web-app for fruitfly expression with added RNA & miRNA goodness ! Click here to visit the application. Read all about it here.

This dataset was generated by Venkat Chintapalli, Jing Wang & Julian Dow at the University of Glasgow with funding from the UK's BBSRC.
It gives you a quick answer to the question: where is my gene of interest expressed/enriched in the adult fly?
For each gene & tissue, you're given the mRNA SIGNAL (how abundant the mRNA is), the mRNA ENRICHMENT (compared to whole flies), and the Affymetrix PRESENT CALL (out of 4 arrays, how many times it was detectably expressed).

String to look for? (e.g. vha, cell adhesion, receptor, aquaporin, adenylate, CG1147, pnt)

Searching for FBGN0010238 through 18771 annotations produced 1 hits

lachesin (Lac):

Annotation Number : CG12369
FlyAtlas2 : Click Here for expression data based on RNA-Seq and or miRNA-Seq analyses
Flybase ID : FBgn0010238
Gbrowse : chr2R:8340695-8353149 (+) // 99.73 //
Probeset : 1628336_a_at
Accessions : protein= NP_523713; /// NP_725173;, nucleotide= NM_078989; /// NM_165906;
Pathway : open tracheal system // inferred from mutant phenotype /// 0035160 // maintenance of epithelial integrity
Interpro : open tracheal system // inferred from mutant phenotype"
FlyMine data for FBgn0010238.
BDGP gene expression has embryonic in situ data for Lac: 91 pix of staining in 43 body parts.
Homophila reports that CG12369 is a close match (3e-12) to human gene DCC (NP_005206), a gene associated with Colorectal cancer (3).
BioGrid reports that CG12369 interacts with CG5846 CG15365 CG4897 CG6287 .
TRiP has 3 RNAi stocks for FBgn0010238 available for purchase.
VDRC has 2 RNAi stocks for FBgn0010238 available for purchase.

TissuemRNA SignalPresent CallEnrichmentAffy Call
Brain248 44 of 4 0.70Down
Head518 274 of 4 1.40Up
Eye467 234 of 4 1.23None
Thoracicoabdominal ganglion144 84 of 4 0.40Down
Salivary gland969 314 of 4 2.54Up
Crop1195 164 of 4 3.10Up
Midgut48 24 of 4 0.10Down
Tubule20 03 of 4 0.10Down
Hindgut736 154 of 4 1.90Up
Heart67 44 of 4 0.18Down
Fat body64 44 of 4 0.17Down
Ovary501 124 of 4 1.30Up
Testis245 124 of 4 0.60Down
Male accessory glands622 344 of 4 1.60Up
Virgin spermatheca183 74 of 4 0.48Down
Mated spermatheca261 294 of 4 0.68Down
Adult carcass404 74 of 4 1.10None
Larval CNS874 554 of 4 2.29Up
Larval Salivary gland896 474 of 4 2.35Up
Larval midgut71 44 of 4 0.19Down
Larval tubule16 34 of 4 0.00Down
Larval hindgut902 204 of 4 2.37Up
Larval fat body172 174 of 4 0.50Down
Larval trachea1569 1134 of 4 4.12Up
Larval carcass605 194 of 4 1.59Up
S2 cells (growing)958 194 of 4 2.51Up
Whole fly381 334 of 4

Looking for FBgn0010238. 1 entries matched from 18771, in 2 s.

Chintapalli, V. R., Wang, J. and Dow, J. A. T. (2007). Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39: 715-720

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